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Last updated on April 21, 2014 at 12:39 EDT

Latest Organelles Stories

Mechanism For Organ Placement Shared By Human Cells, Plants, Worms And Frogs
2012-07-17 10:19:48

New research identifies special protein that determines what goes where As organisms develop, their internal organs arrange in a consistent asymmetrical pattern--heart and stomach to the left, liver and appendix to the right. But how does this happen? Biologists at Tufts University have produced the first evidence that a class of proteins that make up a cell's skeleton -- tubulin proteins -- drives asymmetrical patterning across a broad spectrum of species, including plants, nematode...

2012-07-11 14:36:43

Tracked step for step ATP splitting in membrane protein dynamically measured for the first time RUB researchers report in the Journal of Biological Chemistry How a transport protein obtains its driving force from the energy storage molecule ATP, has been tracked dynamically by RUB researchers. Using time-resolved infrared spectroscopy, they measured the structural changes in the bacterial membrane protein MsbA and its interaction partner ATP. The researchers led by Prof. Dr. Eckhard...

2012-07-05 23:58:43

The findings have implications for the development of new anti-cancer drugs Scientists from the Florida campus of The Scripps Research Institute have identified a series of intricate biochemical steps that lead to the successful production of proteins, the basic working units of any cell. The study, which appears in the July 6, 2012 edition of the journal Cell, sheds light on the assembly of a structure called the ribosome, a large and complex protein-producing machine inside all living...

2012-07-04 22:48:34

Finding biocompatible carriers that can get drugs to their targets in the body involves significant challenges.  Beyond practical concerns of manufacturing and loading these vehicles, the carriers must work effectively with the drug and be safe to consume. Vesicles, hollow capsules shaped like double-walled bubbles, are ideal candidates, as the body naturally produces similar structures to move chemicals from one place to another. Finding the right molecules to assemble into capsules,...

2012-06-12 10:38:23

A small molecule developed at the Weizmann Institute prevents a cancer-causing message from entering the cell nucleus What´s good news in one setting might spell disaster in another. In cancer for instance, when a certain cell is commanded to grow and divide without restraint, it´s a welcome message for the cell itself but a tragedy for the person who harbors this cell in his or her body. Weizmann Institute scientists have managed to decipher and block one type of molecular...

2012-06-11 21:50:23

Researchers work to untangle knots, slipknots in species separated by a billion years of evolution Strings of all kinds, when jostled, wind up in knots. It turns out that happens even when the strings are long strands of molecules that make up proteins. A new study by scientists at Rice University and elsewhere examines structures of proteins that not only twist and turn themselves into knots, but also form slipknots that, if anybody could actually see them, might look like shoelaces...

2012-06-01 09:27:49

New study creates cells that act like circuits, a step toward developing cellular computers Johns Hopkins scientists have engineered cells that behave like AND and OR Boolean logic gates, producing an output based on one or more unique inputs. This feat, published in the May issue of Nature Chemical Biology, could eventually help researchers create computers that use cells as tiny circuits. Study leader Takanari Inoue, Ph.D., an assistant professor in the Department of Cell Biology and...

2012-05-25 10:07:17

Our cells breathe and digest, as does the organism as a whole. They indeed use oxygen to draw the energy contained in the nutrients they ingest, before discarding the waste, as carbon dioxide and water. Glucose is a preferred nutrient for the cells. Its digestion occurs in the cytoplasm, in the absence of oxygen, and leads to the formation of pyruvate and a small amount of energy. Pyruvate is then carried into mitochondria, the cell's power plants, for a complete burning, thus providing a...

2012-05-10 23:14:49

Ribonucleoprotein granules exit the nucleus via a budding mechanism akin to herpes-type viruses The movement of genetic materials, such as RNA and ribosomes, from the nucleus to the cytoplasm is a critical component in a cell's ability to make the proteins necessary for essential biological functions. Until now, it was believed the nuclear pore complex was the sole pathway between the cell nucleus and cytoplasm for these materials. New evidence published in Cell by Vivian Budnik, PhD,...

2012-05-10 13:55:04

Journal of Biological Chemistry: Mechanism of bacterial transport system published In order to interact with the environment, bacteria secrete a whole arsenal of proteins. Researchers have now found how one of the transportation systems used for this purpose — the type VI secretion system — works for the single-celled organism Agrobacterium tumefaciens. They have identified the relevant transport proteins and their energy suppliers. With colleagues at the Academia Sinica in...