Quantcast
Last updated on April 24, 2014 at 21:24 EDT

Latest Organic reactions Stories

2013-11-21 13:11:59

Findings have implications for oncology, diabetes drug development Drugs that inhibit the activity of enzymes called histone deacetylases (HDACs) are being widely developed for treating cancer and other diseases, with two already on the market. Researchers at the Perelman School of Medicine, University of Pennsylvania, show that a major HDAC still functions in mice even when its enzyme activity is abolished, suggesting that the beneficial effects of HDAC inhibitors may not actually be...

2012-08-01 06:21:46

DES PLAINES, Ill., Aug. 1, 2012 /PRNewswire/ -- UOP LLC, a Honeywell (NYSE: HON) company, announced today that it has been selected by Russia's Lukoil to provide technology to produce blending components used to make high-octane gasoline and petrochemicals at its facility in Nizhny Novgorod, Russia. Lukoil will license an integrated suite of Honeywell's UOP technologies to produce high-quality gasoline blending components; propylene, a building block material used in the production of films...

2012-05-01 09:42:57

A team of Stowers scientists defines biochemical crosstalk between DNA interacting proteins and their modifications When stretched out, the genome of a single human cell can reach six feet. To package it all into a tiny nucleus, the DNA strand is tightly wrapped around a core of histone proteins in repeating units–each unit known as a nucleosome. To allow access for the gene expression machinery the nucleosomes must open up and regroup when the process is complete. In the May 1,...

2011-12-28 08:12:12

The findings could point the way to new therapies Scientists at The Scripps Research Institute have discovered that DNA stays too tightly wound in certain brain cells of schizophrenic subjects. The findings suggest that drugs already in development for other diseases might eventually offer hope as a treatment for schizophrenia and related conditions in the elderly. The research, now available online in the new Nature journal, Translational Psychiatry, shows the deficit is especially...

2011-11-04 10:06:00

St. Jude Children's Research Hospital scientists discover that a post-production addition to most proteins can serve as a key to mediate protein interactions, which are at the foundation of life MEMPHIS, Tenn., Nov. 4, 2011 /PRNewswire-USNewswire/ -- Research led by St. Jude Children's Research Hospital scientists has identified an unexpected mechanism facilitating some protein interactions that are the workhorses of cells and, in the process, identified a potential new cancer drug...

2011-04-08 07:00:00

SAN DIEGO, April 8, 2011 /PRNewswire/ -- Polaris Group (Polaris) announced today that data from preclinical studies suggest ADI-PEG 20, the Company's pegylated arginine deiminase therapeutic, may be effective in treating acute myeloid leukemia (AML), glioblastoma multiforme (GBM) and bladder cancer. These cancers have a high incidence of deficiencies of the arginine synthesis enzyme argininosuccinate synthetase (ASS) due to hypermethylation at the promoter of the gene that codes for ASS...

2011-02-01 03:29:00

DALLAS, February 1, 2011 /PRNewswire/ -- According to a new market research report, 'Global Refinery Catalyst Market - FCC ,HTC , HCC by units, geography, ingredients and applications (2010 - 2015)' ( http://www.marketsandmarkets.com/Market-Reports/refinery-catalyst-advanced-te chnologies-and-global-market-84.html), published by MarketsandMarkets (http://www.marketsandmarkets.com), the total global refinery catalyst market is expected to be worth US$3.4 billion by 2015 . The global market...

2011-01-21 14:28:57

Acetylation complex fits like a halo over a histone To understand the emerging science of epigenetics"”a field that describes how genes may be regulated without altering the underlying DNA itself"”scientists are deciphering the many ways in which enzymes act on the proteins surrounding DNA within cells. One type of these enzymes, proteins known as histone acetyltransferases (HATs), act on DNA by modifying DNA-bound proteins called histones. This act of modification, called...

2010-12-16 14:59:57

The function of histones -- the proteins that enable yards of DNA to be crammed into a single cell -- depends on a number of chemical tags adorning their exterior. This sophisticated chemical syntax for packaging DNA into tight little coils or unraveling it again -- called the "histone code" -- is the latest frontier for researchers bent on understanding how genetics encodes life. But recent research from the University of North Carolina at Chapel Hill has found a number of issues with...

2010-11-25 22:17:16

UMass Amherst chemical engineering breakthrough A team of University of Massachusetts Amherst chemical engineers report in today's issue of Science that they have developed a way to produce high-volume chemical feedstocks including benzene, toluene, xylenes and olefins from pyrolytic bio-oils, the cheapest liquid fuels available today derived from biomass. The new process could reduce or eliminate industry's reliance on fossil fuels to make industrial chemicals worth an estimated $400 billion...