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Latest Origin Recognition Complex Stories

New Details Of Biochemical Interactions Necessary For Cell Division Identified
2013-07-15 12:05:33

DOE/Brookhaven National Laboratory Building on earlier work exploring the complex choreography by which intricate cellular proteins interact with and copy DNA prior to cell division, scientists at the U.S. Department of Energy's Brookhaven National Laboratory and collaborators have captured a key step-molecular images showing how the enzyme that unwinds the DNA double helix gets drawn to and wrapped around its target. Details of the research, published in the journal Nature Structural...

2012-03-06 23:03:37

Molecular-level details of mechanism may point to ways to block unwanted cell division Before any cell - healthy or cancerous - can divide, it has to replicate its DNA. So scientists who want to know how normal cells work - and perhaps how to stop abnormal ones - are keen to understand this process. As a step toward that goal, scientists at the U.S. Department of Energy's Brookhaven National Laboratory and collaborators have deciphered molecular-level details of the complex choreography by...

2010-10-08 02:15:08

Accurate duplication of genetic material and the faithful segregation of chromosomes are critical for cell survival. The initiation of DNA replication is linked both to cell cycle progression and chromatin organization. In plants, animals and other "eukaryotes," the assembly of a multi-protein complex called pre-replicative complex (preRC) is the first step in the initiation of DNA replication. As the name implies, origin recognition complex (ORC) proteins bind to origins of DNA replication....


Word of the Day
mallemaroking
  • Nautical, the visiting and carousing of sailors in the Greenland ships.
This word is apparently from a confusion of two similar Dutch words: 'mallemerok,' a foolish woman, and 'mallemok,' a name for some persons among the crew of a whaling vessel.