Latest Orthopoxvirus Stories
DURHAM, N.C., June 27, 2011 /PRNewswire/ -- Chimerix, Inc., a pharmaceutical company developing orally-available antiviral therapeutics, today announced an agreement with the Biomedical Advanced Research and Development Authority (BARDA) of the United States Department of Health and Human Services (HHS) that will resolve the Government Accountability Office (GAO) review of the recent sole source contract awarded to SIGA Technologies, Inc.
In the winter of 1979, the world celebrated the end of smallpox, a highly contagious and often fatal viral infection estimated to have caused between 300 and 500 million deaths during the 20th century.
Researchers report this month that red colobus monkeys in a park in western Uganda have been exposed to an unknown orthopoxvirus, a pathogen related to the viruses that cause smallpox, monkeypox and cowpox. Most of the monkeys screened harbor antibodies to a virus that is similar â€“ but not identical â€“ to known orthopoxviruses.
Vaccinia virus (VACV or VV) is a large, complex, enveloped virus belonging to the poxvirus family. It is well-known for its role in eradicating smallpox. It was the first human disease to to successfully be eradicated by science. The World Health Organization was the one who completed the endeavor. The vaccinia virus saw renewed interest in the early 21st century due to concerns about the smallpox virus being used as an agent for bioterrorism. They can be divided into four types:...