Quantcast
Last updated on April 16, 2014 at 21:24 EDT

Latest Osteoclast Stories

2014-01-31 10:54:35

Scientists at Washington University School of Medicine in St. Louis have discovered what appears to be a potent stimulator of new bone growth. The finding could lead to new treatments for osteoporosis and other diseases that occur when the body doesn't make enough bone. Osteoporosis affects 55 percent of Americans age 50 and older. Of that age group, one in three women and one in 12 men are believed to have osteoporosis, a condition responsible for millions of fractures each year, mostly...

'Reversal Cells' Prepare For Bone Formation During Bone Remodeling
2013-06-06 21:09:31

Elsevier Health Sciences By analyzing biopsy specimens from patients with postmenopausal osteoporosis and primary hyperparathyroidism, investigators have begun to pay increasing attention to "reversal cells," which prepare for bone formation during bone remodeling. The hope is that these reversal cells will become critical therapeutic targets that may someday prevent osteoporosis and other bone disorders. This study is published in the July 2013 issue of The American Journal of Pathology....

2013-04-10 13:24:01

Hardening of the arteries, or atherosclerosis, is the primary cause of heart disease. It is caused by calcium accumulation in the blood vessels, which leads to arteries becoming narrow and stiff, obstructing blood flow and leading to heart complications. Although many risk factors for atherosclerosis have been identified, the cause is not known and there is currently no way to reverse it once it sets in. In a new study published 9th April in the open access journal PLOS Biology, researchers...

2013-02-06 10:59:33

New research in animals triggered by a combination of serendipity and counterintuitive thinking could point the way to treating fractures caused by rapid bone loss in people, including patients with metastatic cancers. A series of studies at the University of North Carolina School of Medicine found that steroid drugs, known for inducing bone loss with prolonged use, actually help suppress a molecule that's key to the rapid bone loss process. A report of the new findings appears online Feb....

2011-10-04 12:22:30

Researchers identify a new gene that could help identify individuals predisposed to developing the disease Researchers at the Institut de recherches cliniques de Montréal (IRCM), directed by Dr. Jean Vacher, identified a new gene that modulates bone mass and that could become a risk factor for developing osteoporosis. This scientific breakthrough will be published tomorrow in the scientific journal Cell Metabolism. Osteoporosis is a "silent" genetic disease characterized by...

2011-03-14 16:19:56

New research shows that the Wnt receptor Frizzled-9 (Fzd9) promotes bone formation, providing a potential new target for the treatment of osteoporosis. The study appears online on March 14 in The Journal of Cell Biology (www.jcb.org). Adult bones are maintained by a balance of bone-forming osteoblasts and bone-resorbing osteoclasts. Although Wnt signaling affects this balance in mice and humans, the Wnt receptors involved remain unknown. A team of researchers led by Thorsten Schinke found...

2011-01-14 19:08:51

A gene from the measles virus plays a key role in the development of Paget's disease of bone, according to a team of researchers led by the University of Pittsburgh School of Medicine. Their findings, recently published in Cell Metabolism, confirm a long-held speculation that the childhood infection is an environmental trigger for the disease and reveal how the viral gene contributes to the development of its characteristic bone lesions. "Our earlier work showed that bone cells called...

bc6aa9b63696d829fc1488168bbb110f1
2010-03-31 13:39:28

The "vegetable lamb" plant "” once believed to bear fruit that ripened into a living baby sheep "” produces substances that show promise in laboratory experiments as new treatments for osteoporosis, the bone-thinning disease. That's the conclusion of a new study in ACS' monthly Journal of Natural Products. Young Ho Kim and colleagues point out that osteoporosis is a global health problem, affecting up to 6 million women and 2 million men in the United States alone. Doctors know...

2009-12-16 04:26:00

PUTEAUX, France, December 16 /PRNewswire/ -- - Studies Conducted at INRA-Agroparistech Laboratory Under Pr. Daniel Tome's Supervision and Published* in November 2009, in the Official Journal of the International Bone and Mineral Society "Bone", Reveal new Benefits for Peptan(TM) in Osteoporosis Prevention In response to consumer concerns regarding long-term bone health, Rousselot has carried out, for several years now, many studies to demonstrate that an oral intake of...

81d2b57fa3f67a54dac4362f71ba81bf1
2009-10-14 15:15:10

The "vegetable lamb" plant "” once believed to bear fruit that ripened into a living baby sheep "” produces substances that show promise in laboratory experiments as new treatments for osteoporosis, the bone-thinning disease. That's the conclusion of a new study in ACS' monthly Journal of Natural Products. Young Ho Kim and colleagues point out that osteoporosis is a global health problem, affecting up to 6 million women and 2 million men in the United States alone. Doctors know...