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Last updated on April 18, 2014 at 6:03 EDT

Latest Oxaliplatin Stories

2012-08-03 10:21:33

PARIS and TARRYTOWN, N.Y., Aug. 3, 2012 /PRNewswire/ -- Sanofi (EURONEXT: SAN and NYSE: SNY) and Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) today announced that the U.S. Food and Drug Administration (FDA) approved ZALTRAP(®) (ziv-aflibercept) Injection for Intravenous Infusion, in combination with 5-fluorouracil, leucovorin, irinotecan (FOLFIRI), for patients with metastatic colorectal cancer (mCRC) that is resistant to or has progressed following an oxaliplatin-containing regimen....

2012-04-04 18:20:13

PARIS and TARRYTOWN, N.Y., April 5, 2012 /PRNewswire/ -- Sanofi (EURONEXT: SAN and NYSE: SNY) and Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) today announced that the U.S. Food and Drug Administration (FDA) has granted Priority Review of the Biologics License Application (BLA) for the investigational agent ZALTRAP® (aflibercept) concentrate for solution for infusion in combination with the irinotecan-fluoropyrimidine-based chemotherapy in patients with metastatic colorectal cancer...

2012-04-04 10:14:06

Adding the drug cetuximab to a regimen of drugs used for the treatment of patients following surgery for stage III colon cancer did not result in improved disease-free survival, according to a study in the April 4 issue of JAMA. Patients who have surgery for removal of stage III colon cancer have a 50 percent chance of cure. Multiple trials have established the benefit of chemotherapy after surgery in reducing the recurrence risk. "Specifically, [the drugs] leucovorin, fluorouracil, and...

2012-03-28 02:25:17

VANCOUVER, March 28, 2012 /PRNewswire/ - Allon Therapeutics Inc. (TSX: NPC) announced today that it has been granted a U.S. patent that covers the use of the Company's neuroprotective technology platform in the treatment of peripheral neuropathy. This includes the Company's lead drug candidate, davunetide, and pipeline product AL-309 as treatments for peripheral neuropathy caused by anti-cancer drugs. Dr. Alistair Stewart, Allon's Vice President of Commercial Research, said the...

2012-02-03 12:58:03

The drug oxaliplatin is a major reason the prognosis for metastatic colon cancer has gone from an expected survival of several months to a couple years. Unfortunately, the drug can also carry with it debilitating neurological side effects, which generally start as the sensation of pins and needles in fingers and toes and can leave patients unable to walk or dress independently. However, “Many patients don´t receive the necessary dose to try to keep their cancer in check, because...

2012-01-12 15:31:00

CAMBRIDGE, Mass., Jan. 12, 2012 /PRNewswire/ -- Merrimack Pharmaceuticals, Inc. announced today that Phase 1 results on MM-398, one of its five targeted therapeutic oncology candidates in clinical development, will be presented at the ASCO 2012 Gastrointestinal Cancers Symposium being held January 19 - 21, 2012, in San Francisco, CA. MM-398 MM-398 is a novel, stable nanotherapeutic encapsulation of irinotecan. The U.S. Food and Drug Administration (FDA) has granted MM-398 orphan...

2011-11-15 07:27:00

THOUSAND OAKS, Calif., Nov. 15, 2011 /PRNewswire/ -- Amgen (NASDAQ: AMGN) today announced that the European Commission (EC) has approved a variation to the marketing authorization for Vectibix® (panitumumab) to include indications for the treatment of patients with wild-type KRAS metastatic colorectal cancer (mCRC) in first-line in combination with FOLFOX and in second-line in combination with FOLFIRI in patients who have received first-line fluoropyrimidine-based...

2011-11-15 05:00:00

HOBOKEN, N.J. and PHILADELPHIA, Nov. 15, 2011 /PRNewswire/ -- Niiki Pharma Inc. presented the results of preclinical combination studies of its lead product, NKP-1339, at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics held in San Francisco, CA, November 12-16, 2011. The data were presented as a poster, titled "NKP-1339 synergistic activity in both in vitro and in vivo preclinical models highlights the therapeutic opportunity for NKP-1339...

2011-11-02 08:00:00

BOZEN, SUD-TIROL, Italy, November 2, 2011 /PRNewswire/ -- Health Robotics announced that CytoCare and Japan-based Tosho Inc. recently won a public tender purchasing process, sponsored by the Oxaliplatin Fund, at prestigious Nagoya City University Hospital's Cancer Center http://www.med.nagoya-cu.ac.jp/w3med/en/index.html Nagoya City University Hospital is one of the most influential Oncology hospitals in Asia-Pacific, and the birthplace (1976) of Oxaliplatin, a...

2011-09-28 12:44:44

Nerve degeneration detected with skin biopsies Oxaliplatin, a platinum-based anticancer drug that's made enormous headway in recent years against colorectal cancer, appears to cause nerve damage that may be permanent and worsens even months after treatment ends. The chemotherapy side effect, described by Johns Hopkins researchers in the September issue of Neurology, was discovered in what is believed to be the first effort to track oxaliplatin-based nerve damage through relatively cheap...