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2010-11-17 17:38:56

When cardiac or skeletal muscle is not receiving enough oxygen to meet metabolic demands, a person will experience pain, such as angina, chest pain during a heart attack, or leg pain during a vigorous sprint. This type of pain is called "ischemic" pain and is sensed in the body by receptors on sensory neurons. It has been suggested that lactic acid, which increases during muscle exertion under conditions where oxygen is low, is a potential mediator of ischemic pain via action at acid sensing...


Word of the Day
out-herod
  • In the phrase to out-herod Herod, to be more violent than Herod (as represented in the old mystery plays); hence, to exceed in any excess of evil.
Herod refers to 'Herod the Great,' a Roman client king and 'a madman who murdered his own family and a great many rabbis.' According to the OED, the term is 'chiefly with allusion to Shakespeare's use' in Hamlet.
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