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Last updated on April 23, 2014 at 16:13 EDT

Latest P53 Stories

2011-10-05 03:00:00

LAUSANNE, Switzerland, October 5, 2011 /PRNewswire/ -- Debiopharm Group(TM) (Debiopharm), a Swiss-based global biopharmaceutical group with a focus on drug development and companion diagnostics, today presented the 'JCA-Mauvernay Award' to Doctor Hirofumi Arakawa from the National Cancer Center Research Institute in Tokyo, for his basic research on the 'identification and characterization of p53 target genes' and to Doctor Mineo Kurokawa from the University of Tokyo, for his...

2011-09-27 11:35:01

First comprehensive assessment of DNA errors that drive advanced prostate cancer A team of researchers at Fred Hutchinson Cancer Research Center and the University of Washington has conducted the first comprehensive assessment of every gene in the genome of advanced, lethal prostate cancer. Until now, the genetic composition of such tumors had been poorly defined. In the process, they have discovered a number of potential key drivers — recurrent genetic mistakes — common to...

2011-09-25 12:05:00

REYKJAVIK, Iceland, September 25, 2011 /PRNewswire/ -- Scientists at deCODE Genetics and academic collaborators from Iceland, The Netherlands, Spain, Denmark, Germany, Sweden, the USA, the UK and Romania today report the discovery of a variant in the sequence of the human genome associated with risk of developing basal cell carcinoma of the skin (BCC), as well as prostate cancer and glioma, the most serious form of brain cancer. The study was done in collaboration with Illumina,...

2011-09-13 06:00:00

KIRKLAND, Wash., Sept. 13, 2011 /PRNewswire/ -- Regenerative Cellular Therapy (RCT) of Puerto Penasco, Sonora, Mexico, is holding its first annual treatment giveaway. Over the next five weeks, starting September 13, two lucky winners per week will receive state-of-the-art regenerative cellular cancer treatments free of charge. The winners will be selected at random in five weekly lottery drawings. Any cancer sufferer may enter by submitting an online form, at...

2011-09-07 13:48:10

The protein p53 plays an essential role in the prevention of cancer by initiating the controlled death of a cell with damaged genes which is in danger to transform into a cancerous cell. The heat shock protein Hsp90, in turn, activates and stabilizes p53. Now scientists of the Technische Universität München (TUM) have discovered both the site where the two proteins interact and the interaction mechanism. The results of their work are reported in the current...

2011-08-16 12:19:04

Tumors that do not respond to chemotherapy are the target of a cancer therapy that prevents the function of two enzymes in mouse tumor cells, according to Pennsylvania medical researchers. "We've known for well over a decade that when tumors become hypoxic they become resistant to chemotherapy and radiotherapy," said Wafik S. El-Deiry, M.D. Ph.D., American Cancer Society Research Professor, Rose Dunlap Professor and chief of hematology/oncology, Penn State College of Medicine. "This is a huge...

2011-07-28 23:28:00

Centers collaborate to reveal unexpected genetic mutations Powerful new technologies that zoom in on the connections between human genes and diseases have illuminated the landscape of cancer, singling out changes in tumor DNA that drive the development of certain types of malignancies such as melanoma or ovarian cancer. Now several major biomedical centers have collaborated to shine a light on head and neck squamous cell cancer. Their large-scale analysis has revealed a surprising new set of...

2011-07-19 13:20:54

Scientists at the Keck School of Medicine of USC grow brain cells from skin Oncogenes are generally thought to be genes that, when mutated, change healthy cells into cancerous tumor cells. Scientists at the Keck School of Medicine of the University of Southern California (USC) have proven that those genes also can change normal cells into stem-like cells, paving the way to a safer and more practical approach to treating diseases like multiple sclerosis and cancer with stem cell therapy. "The...

2011-07-15 14:23:16

A protein that appears to play a key role in the formation of lymphoma and other tumors by inhibiting a tumor-suppressing gene has been identified by a team of veterinary and human medicine researchers at the University of California, Davis. The researchers suggest that the newly identified protein may be a potential target for diagnosing and treating lymphoma in humans and animals. They will report their findings July 15 in the journal Genes & Development. "Results from this study...

2011-07-15 07:20:39

(Ivanhoe Newswire) "“ According to the Leukemia and Lymphoma Society, over 21,000 Americans died from lymphoma cancer last year. Lymphoma refers to a group of blood cancers that start in the lymphatic system, a network of lymph vessels and lymph nodes that play a vital role in the body's immune system. Researchers believe that a newly identified protein may be a potential target for diagnosing and treating lymphoma in humans and animals. The protein appears to play a key role in the...