Latest P53 Stories
IRVINE, California, and AMSTERDAM, December 22, 2010 /PRNewswire/ -- - This release was originally scheduled for distribution on December 20, 2010, 17.00 CET.
The recently identified TRIM24 protein plays an active role in pushing normal breast cells into rapid cell proliferation and, potentially, into breast cancer.
In studies conducted on the fruit fly, researchers at IRB Barcelona headed by ICREA Professor Marco MilÃ¡n have revealed that organs have the molecular mechanisms to control their proportions.
A close collaboration between researchers at the Salk Institute for Biological Studies and the Institute for Advanced Study found that the tumor suppressor p53, long thought of as the "Guardian of the Genome," may do more than thwart cancer-causing mutations.
First clinical trial looks at RG7112 as a way to disable MDM2 in leukemia.
Although p53 is called the â€œguardian of the genomeâ€, having the job of preventing defective cells from dividing, some cancer cells have found a loop hole.
SAN DIEGO, Nov. 16, 2010 /PRNewswire/ -- Cylene Pharmaceuticals, Inc. will present advances in the development of their first-in-class, CK2 inhibitor CX-4945, at the 22nd EORTC-NCI-AACR symposium on Molecular Targets and Cancer Therapeutics, to be held on November 16-19 in Berlin, Germany.
It is common for cancer cells to find some way to disarm p53, also known as "guardian of the genome" due to its action in preventing defective cells from dividing.
New research links three molecules to a critical tumor suppressor gene that is often turned off in multiple myeloma, a presently incurable cancer of the blood.
Long overshadowed by p53, its famous tumor-suppressing sibling, the p63 gene does the tougher, important job of stifling the spread of cancer to other organs.
- A trick or prank.