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Last updated on April 19, 2014 at 7:50 EDT

Latest P53 Stories

2013-12-09 10:16:39

Certain genetic alterations to the PAX gene family may be responsible for survival disparities seen between African-American and non-Latino white men with head and neck cancer, according to results presented here at the Sixth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held Dec. 6-9. "During the last 30 years, the overall five-year relative survival rates for head and neck squamous cell carcinoma (HNSCC) have...

2013-10-21 08:28:36

ROCKVILLE, Md., Oct. 21, 2013 /PRNewswire/ -- EntreMed, Inc. (NASDAQ:ENMD), a clinical-stage pharmaceutical company developing therapeutics for the treatment of a variety of cancers, announced today the presentation of preclinical data from a study to assess the role of p53 family tumor suppressors in mediating response to ENMD-2076 in triple-negative breast cancer (TNBC). The study was led by Dr. Jennifer R. Diamond of University of Colorado and the results were presented at the...

2013-10-18 13:26:56

A gene important in skin tanning has been linked to higher risk for testicular cancer in white men, according to a study led by scientists from the U.S. National Institutes of Health and the University of Oxford in England. Nearly 80 percent of white men carry a variant form of this gene, which increased risk of testicular cancer up to threefold in the study. The research appeared online October 10, 2013 in the journal Cell, and is the result of an integrated analysis of big data supported...

Genetic Variation Fuels Testicular Cancer
2013-10-11 04:33:32

Brett Smith for redOrbit.com - Your Universe Online Using a genomic analysis, a team of international researchers has identified a specific mutation responsible for a dramatic increase in the risk for testicular cancer. The mutation is a single-base change to the genetic code that affects the activity of the p53 protein that is responsible for regulating the activity of a large number of genes, including those responsible for protection from UV rays – according to the team’s report...

Study Shows Sunscreen Provides 100 Percent Protection Against Skin Cancer
2013-10-08 17:32:11

Lee Rannals for redOrbit.com – Your Universe Online Sunscreen not only helps prevent three types of skin cancer, it also shields a ‘superhero’ gene that repairs sun-damaged skin. Scientists performing the world's first human study to assess the impact of sunscreen at the molecular level have confirmed that the skin protector provides 100 percent protection against all three-forms of skin cancer, including basal cell carcinoma, squamous cell carcinoma, and malignant melanoma....

2013-10-07 09:22:06

In a study published in published in EMBO Molecular Medicine, a Dartmouth researcher found that dying heart cells are kept alive with spikes of oxygen. During a heart attack when the flow of oxygen-rich blood to a section of the heart is interrupted, and not quickly restored, heart muscle begins dying. Deprived of oxygen and other essential nutrients, cell death continues occurring over a period of time leading to progressive loss of heart function and congestive heart failure. Current...

Macular Degeneration Treatment Hope
2013-09-15 04:15:49

Brett Smith for redOrbit.com - Your Universe Online According to a new study published in the Journal of Clinical Investigation, medical researchers at the University of North Carolina are developing a promising new treatment for macular degeneration. Based on experiments with laboratory mice, a group of drugs known as MDM2 inhibitors proved exceedingly effective at mitigating the abnormal blood vessels responsible for the vision loss linked to the disease. “We believe we may have...

2013-09-13 23:03:02

Study Reveals Network of Genes that Safeguard Cooperation in Stem Cells and the Developing Embryo New York, NY (PRWEB) September 13, 2013 We often think of human cells as tiny computers that perform assigned tasks, where disease is a result of a malfunction. But in the current issue of Science, researchers at The Mount Sinai Medical Center offer a radical view of health — seeing it more as a cooperative state among cells, while they see disease as result of cells at war that fight...

2013-07-11 16:34:59

Salk researchers' findings on chromosome shortening suggest a potential target to arrest cancer cell growth A team of scientists at the Salk Institute for Biological Studies has identified why disruption of a vital pathway in cell cycle control leads to the proliferation of cancer cells. Their findings on telomeres, the stretches of DNA at the ends of chromosomes that protect our genetic code and make it possible for cells to divide, suggest a potential target for preventive measures...

2013-05-19 23:01:26

Australian Researchers Astonished to Learn P53 Not Only Seeks and Destroys, But Prevents DALLAS (PRWEB) May 19, 2013 Scientists are on the verge of unraveling the genesis of cancer. By studying the behavior of distorted genes in the malignant microenvironment (inside the body) studies are attempting to recode damaged gene signals so the body´s immune system can search and destroy cancer. But that´s not all. 1 P53 protein has long been the subject of intense investigation because...