Latest P73 Stories
Aggressive tumors lacking p53 protein stop dead in their tracks when p53's sister protein -- TAp63 -- steps in.
Researchers say they may have discovered the way a particular gene regulates the development of tumors.
U.S. researchers say they have linked a genetic variant of a protein to resistance to the chemotherapy drug cisplatin.
Researchers have discovered a key regulatory molecule whose overactivation by the abnormal protein produced in Huntington's disease (HD) causes the central pathologies of the disease. The abnormal HD protein activates the regulatory protein called p53, which in turn switches on a host of other genes. This abnormal gene activation damages the cells' power plants, called the mitochondria, and kills brain cells.