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Latest PAC-1 Stories

48696f007930a9a6f35f9fa6c46524bf
2010-09-07 14:22:45

Researchers have identified a new target for the treatment of lymphoma and are testing a potential new drug in pet dogs afflicted with the disease. At low doses, the compound, called S-PAC-1, arrested the growth of tumors in three of six dogs tested and induced partial remission in a fourth. The results of the study, conducted by researchers at the University of Illinois, appear this month in the journal Cancer Research. The new compound targets a cellular enzyme, procaspase-3, that when...

2005-10-21 19:16:12

Richmond, Va. (Oct. 21, 2005) "” A team of researchers at Virginia Commonwealth University Massey Cancer Center has discovered an entirely new mechanism of action for a novel pharmacological agent currently in clinical trials in patients "“ the kinase inhibitor BAY 43-9006 "“ which was designed to disrupt the survival pathways of tumor cells. "This agent was originally designed to inhibit the Raf-1 pathway, which is frequently mutated in many types of cancers, including...


Word of the Day
attercop
  • A spider.
  • Figuratively, a peevish, testy, ill-natured person.
'Attercop' comes from the Old English 'atorcoppe,' where 'atter' means 'poison, venom' and‎ 'cop' means 'spider.' 'Coppa' is a derivative of 'cop,' top, summit, round head, or 'copp,' cup, vessel, which refers to 'the supposed venomous properties of spiders,' says the OED. 'Copp' is still found in the word 'cobweb.'
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