Latest PAC-1 Stories

2010-09-07 14:22:45

Researchers have identified a new target for the treatment of lymphoma and are testing a potential new drug in pet dogs afflicted with the disease. At low doses, the compound, called S-PAC-1, arrested the growth of tumors in three of six dogs tested and induced partial remission in a fourth. The results of the study, conducted by researchers at the University of Illinois, appear this month in the journal Cancer Research. The new compound targets a cellular enzyme, procaspase-3, that when...

2005-10-21 19:16:12

Richmond, Va. (Oct. 21, 2005) "” A team of researchers at Virginia Commonwealth University Massey Cancer Center has discovered an entirely new mechanism of action for a novel pharmacological agent currently in clinical trials in patients "“ the kinase inhibitor BAY 43-9006 "“ which was designed to disrupt the survival pathways of tumor cells. "This agent was originally designed to inhibit the Raf-1 pathway, which is frequently mutated in many types of cancers, including...

Word of the Day
  • A rich embroidered or brocaded silk fabric woven originally with a warp of gold thread.
'Baudekin' seems to be an alternative form of 'baldachin,' from the Italian 'Baldacco,' Baghdad, the city where the material was made.