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Latest Paget's disease of bone Stories

2012-06-12 23:01:41

A study published online in May 2012, by the Archives of Internal Medicine, a publication of the American Medical Association, revealed that atypical femoral fractures were associated with bisphosphonate (including Fosamax) use. Fosamax, manufactured by Merck, belongs to the class of drugs known as bisphosphonates. It was approved by the FDA in 1995 and developed to treat post-menopausal osteoporosis and Paget's disease of bone. On March 3rd, 2010, the U.S FDA issued a drug safety...

2012-03-09 13:25:00

According to court documents, on February 27th, 2012, a jury trial began in the Superior Court for Atlantic County, New Jersey in In re: Fosamax Litigation (No. 282). Plaintiffs allege that their Fosamax use caused them to develop osteonecrosis of the jaw (ONJ). Fosamax, manufactured by Merck, is a drug approved by the FDA in 1995 to treat post-menopausal osteoporosis and Paget's disease of bone. ONJ is a rare bone disease that can cause the patient's jaw bone to deteriorate and die. The...

2011-01-14 19:08:51

A gene from the measles virus plays a key role in the development of Paget's disease of bone, according to a team of researchers led by the University of Pittsburgh School of Medicine. Their findings, recently published in Cell Metabolism, confirm a long-held speculation that the childhood infection is an environmental trigger for the disease and reveal how the viral gene contributes to the development of its characteristic bone lesions. "Our earlier work showed that bone cells called...

2010-10-16 15:45:00

EAST HANOVER, N.J., Oct. 16 /PRNewswire/ -- Novartis announced today that new six-year data reinforce the long-term efficacy and safety profile of once-yearly Reclast® (zoledronic acid) injection in postmenopausal women with osteoporosis.(1) The study of more than 1,200 women was presented this weekend at the annual meeting of the American Society for Bone and Mineral Research (ASBMR) in Toronto, ON, Canada. The study showed that Reclast maintained bone mass in...

2010-09-14 18:32:36

Expert panel calls for additional product labeling, international patient registry A widely prescribed class of drugs is highly effective in reducing common bone fractures in people with osteoporosis, but an expert panel announced today that these same drugs "“ when used long term "“ may be related to unusual but serious fractures of the thigh bone. In the most comprehensive scientific report to date on the topic, the task force reviewed 310 cases of "atypical femur fractures,"...

2010-05-03 10:40:06

Scientists have discovered three genes linked to the development of Paget's disease, a painful bone condition that affects up to one million people in the UK. The international team of scientists, led by the University of Edinburgh, believes the genes are involved in regulating the rate at which bone is repaired, providing an explanation of why the disease might occur. Paget's disease disrupts the body's normal process of breaking down old bone and replacing it. The condition leads to...


Word of the Day
tessitura
  • The prevailing range of a vocal or instrumental part, within which most of the tones lie.
This word is Italian in origin and comes from the Latin 'textura,' web, structure.