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Latest Paget's disease Stories

2012-07-31 10:25:18

OTTAWA, July 31, 2012 /CNW/ - Health Canada is informing Canadians that it is assessing the possibility of an increased risk of cancer with long-term use of the drug calcitonin. Calcitonin is a prescription drug available in Canada as a nasal spray used to treat osteoporosis (loss of calcium in bones) in postmenopausal women. It is also available as a solution for injection used to treat Paget's disease as well as severe hypercalcemia (high blood calcium). Paget's disease is a...

2011-01-14 19:08:51

A gene from the measles virus plays a key role in the development of Paget's disease of bone, according to a team of researchers led by the University of Pittsburgh School of Medicine. Their findings, recently published in Cell Metabolism, confirm a long-held speculation that the childhood infection is an environmental trigger for the disease and reveal how the viral gene contributes to the development of its characteristic bone lesions. "Our earlier work showed that bone cells called...

2010-05-03 10:40:06

Scientists have discovered three genes linked to the development of Paget's disease, a painful bone condition that affects up to one million people in the UK. The international team of scientists, led by the University of Edinburgh, believes the genes are involved in regulating the rate at which bone is repaired, providing an explanation of why the disease might occur. Paget's disease disrupts the body's normal process of breaking down old bone and replacing it. The condition leads to...

2008-07-10 06:00:13

By Kelsey, Jennifer L Lamster, Ira B Both musculoskeletal disorders and diseases of the oral cavity are common and potentially serious problems among older persons, yet little attention has been given to the links between them. Several musculoskeletal diseases, including osteoporosis, Paget's disease, and arthritic disorders, may directly involve the oral cavity and contiguous structures. Drugs used to treat musculoskeletal diseases, including corticosteroids and bisphosphonates, increase...

2004-11-29 12:00:19

NEW YORK, Nov. 29 /PRNewswire/ -- The Paget Foundation announces its endorsement of Bone Health and Osteoporosis: A Report of the Surgeon General issued on October 14th by Surgeon General Richard H. Carmona, M.D. This report marks the first report by the Surgeon General on the topic of bone health and diseases, including Paget's disease, the second most prevalent bone disease after osteoporosis. "The Surgeon General's report provides important information about the causes, clinical features...