Latest Pancreatic stellate cell Stories
Tumors can arise from different cell types in the pancreas Study results: MIT cancer biologists have identified a subpopulation of cells that can give rise to pancreatic cancer. They also found that tumors can form in other, more mature pancreatic cell types, but only when they are injured or inflamed, suggesting that pancreatic cancer can arise from different types of cells depending on the circumstances. Why it matters: There are few good treatment options for pancreatic cancer, which kills...
Fibrosis is a key feature of chronic pancreatitis and pancreatic cancer. The extensive deposition of extracellular matrix proteins fosters the development of an exocrine and endocrine organ insufficiency, and accelerates progression of the tumor. Pancreatic stellate cells (PSC) are the principal effector cells in pancreatic fibrosis. They are activated by profibrogenic mediators, which include, for example, cytokines and ethanol metabolites. So far, there are no therapies available to...
- Remarkable; prodigious.
- Audacious; gutsy.
- Completely; extremely.
- Audaciously; boldly.
- Impressively great in size; enormous; extraordinary.