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Latest Paracetamol toxicity Stories

2014-04-10 13:40:50

In the UK paracetamol toxicity is the most common cause of ALF and has a high mortality rate. It is estimated that 150 to 200 deaths and 15 to 20 LTs occur as a result of poisoning each year in England and Wales. LT is the definitive treatment for ALF patients who meet the criteria for transplantation but the current means of selection for LT (the King's College Criteria) are not ideal and do not assess changes in prognostic measures over time or quantify the mortality risk for individual...

2013-02-08 11:51:51

But researchers warn that further measures required to limit death toll Long term effect of reduced pack sizes of paracetamol on poisoning deaths and liver transplant activity in England and Wales: interrupted time series analysis The number of deaths and liver transplants due to paracetamol overdoses has significantly reduced thanks to UK legislation to make pack sizes smaller, a paper published today on bmj.com suggests. Paracetamol overdoses are a common method of suicide and...

2012-06-06 05:33:33

(Ivanhoe Newswire) — Acetaminophen, a widely available over-the-counter medication, can cause liver toxicity in children if doses are exceeded. It is the most common single agent responsible for a life-threatening event, longer-term illness or death. “Acetaminophen overdose is a major cause of acute liver failure and is the most common identifiable cause of acute liver failure in children,” Dr. Rod Lim of the Department of Pediatrics at the Children´s Hospital in...

2012-02-27 07:25:57

New way for doctors to predict who needs liver transplants University of Utah mathematicians developed a set of calculus equations to make it easier for doctors to save Tylenol overdose patients by quickly estimating how much painkiller they took, when they consumed it and whether they will require a liver transplant to survive. "It's an opportunity to use mathematical methods to improve medical practice and save lives," says Fred Adler, a professor of mathematics and biology and...

2011-11-23 11:33:25

Repeatedly taking slightly too much paracetamol over time can cause a dangerous overdose that is difficult to spot, but puts the person at danger of dying. Patients may not come to hospital reporting the overdose, but because they feel unwell. This clinical situation needs to be recognized and treated rapidly because these patients are at even greater danger than people who take single overdoses. These so-called staggered overdoses can occur when people have pain and repeatedly take a...

2011-09-02 11:30:23

Researchers identify possible new therapeutic target for acetaminophen induced acute liver failure NYU School of Medicine researchers have discovered that dendritic cells in the liver have a protective role against the toxicity of acetaminophen, the widely used over-the-counter pain reliever and fever reducer for adults and children. The study's findings are published in the September issue of the journal Hepatology. The liver is the organ that plays a central role in transforming and...

2011-05-19 11:27:43

Many of the prescriptions issued by GPs for paracetamol either give less than recommended doses to older children or exceed recommended doses in young children. Under-dosing may result in insufficient pain relief and over-dosing can damage a person's liver. "Getting the dose right can become even more complicated when parents also give their children additional paracetamol that they have bought over the counter," says James McLay, a senior member of the research team who studied this issue....

2010-09-17 13:58:35

Research at the University of Liverpool could lead to faster and more accurate diagnoses of liver damage. The team used paracetamol as the basis for the study: research indicates that paracetamol can place temporary stress on the liver in around a third of people who take a normal dose (4g per day) but the liver returns to normal when the drug has left the system. Overdoses of the drug are a major cause of liver failure in both the UK and US. Scientists have discovered that the presence of...

2010-05-11 11:15:00

NASHVILLE, Tenn., May 11 /PRNewswire-FirstCall/ -- Cumberland Pharmaceuticals Inc. (Nasdaq: CPIX) and Phebra Pty Ltd. today announced that Acetadote® (acetylcysteine) Injection has been granted regulatory approval for marketing and sale in Australia. Acetadote, an injectable drug used to treat acetaminophen (paracetamol) overdose, was approved by the Therapeutic Goods Administration (TGA), the government agency responsible for regulating drugs and medical devices in...


Word of the Day
endocarp
  • The hard inner (usually woody) layer of the pericarp of some fruits (as peaches or plums or cherries or olives) that contains the seed.
This word comes from the Greek 'endon,' in, within, plus the Greek 'kardia,' heart.
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