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Latest Parkin Stories

2013-12-18 11:47:56

Dopamine-producing cells die as result of cascade triggered by busy enzyme degradation cellular machines Scientists have identified the biological pathway that explains Gaucher disease (GD) patients' higher risk for developing Parkinson's disease (PD), according to research to be presented Tuesday, Dec. 17, at the American Society for Cell Biology annual meeting in New Orleans. GD is a hereditary disease in which the genes that encode the enzyme glucocerebrosidase are mutated, resulting...

2013-11-04 15:31:05

Non-motor symptoms, including abnormalities in cognition, mental behaviors, autonomic nerves and sensory perception, have the greatest effect on the quality of in Parkinson's disease patient life. Voxel-based morphometry can be used to quantitatively compare structural differences and func-tional changes of gray matter in subjects. According to a study, Gray matter images of 32 Parkinson's disease patients and 25 healthy controls were compared using voxel-based morphometry to investigate the...

2013-10-28 23:29:48

Kindred Box Offers New Approach to Charitable Giving With Subscription Box Service Orlando, FL (PRWEB) October 28, 2013 A new non-profit aims to change the way donations are made. The organization, Kindred Box, acts as a subscription service that would aggregate donations and give them to a different charity each month. In exchange, participants receive a box with a handwritten thank you note and information on the impact their donation has generated. All donations are tax deductible....

2013-10-02 12:51:46

Results presented at World Parkinson Congress Researchers at the University of Montreal and the Institut universitaire de gératrie de Montréal examined brain changes over 20 months in Parkinson's patients with and without mild cognitive impairment (MCI) at the early stages of the disease. Results showed that patients with MCI had significantly more cortical thinning and subcortical atrophy over time compared with patients without MCI, suggesting that early MCI in PD patients may indicate...

2013-09-19 10:16:34

A genetic mutation, known as GBA, that leads to early onset of Parkinson's disease and severe cognitive impairment (in about 4 to 7 percent of all patients with the disease) also alters how specific lipids, ceramides and glucosylceramides are metabolized. Mayo Clinic researchers have found that Parkinson's patients who do not carry the genetic mutation also have higher levels of these lipids in the blood. Further, those who had Parkinson's and high blood levels were also more likely to have...

2013-08-26 11:26:49

Compounds already exist to potentially treat both inherited and non-inherited cases Researchers at Johns Hopkins and elsewhere have brought new clarity to the picture of what goes awry in the brain during Parkinson's disease and identified a compound that eases the disease's symptoms in mice. Their discoveries, described in a paper published online in Nature Neuroscience on August 25, also overturn established ideas about the role of a protein considered key to the disease's progress....

2013-08-12 14:10:30

Researchers have discovered how genetic mutations linked to Parkinson's disease might play a key role in the death of brain cells, potentially paving the way for the development of more effective drug treatments. In the new study, published in Nature Neuroscience, a team of researchers from UCL, the University of Cambridge and the University of Sheffield showed how defects in the Parkinson's gene Fbxo7 cause problems with 'mitaphagy' – an essential process through which our bodies are...

2013-08-06 09:13:17

A study by Valentina Moskvina, Ph.D., of the Cardiff University School of Medicine, Wales, United Kingdom, and colleagues, examined the genetic overlap between Parkinson disease (PD) and Alzheimer disease (AD). Data sets from the United Kingdom, Germany, France and the United States were used to perform a combined genome-wide association analysis (GWA). The GWA study of AD included 3,177 patients with AD and 7,277 control patients, and the GWA analysis for PD included 5,333 patients with...


Word of the Day
bibliopole
  • A bookseller; now, especially, a dealer in rare and curious books.
This word comes from a Greek phrase meaning 'book seller.'
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