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Latest Parkin Stories

2012-06-27 07:05:57

Long-term aim is to develop new treatments to block the spread of damaged proteins in the brain Grand Rapids, Mich. (June 27, 2012) — Van Andel Institute announces that researchers at Lund University in Sweden have published a study detailing how Parkinson's disease spreads through the brain. Experiments in rat models uncover a process previously used to explain mad cow disease, in which misfolded proteins travel from sick to healthy cells. This model has never before been identified...

2012-06-04 19:32:43

Researchers at the University of Toronto Scarborough (UTSC) used an innovative technique to examine chemical interactions that are implicated in Parkinson's Disease. The work details how a protein called alpha-synuclein interacting with the brain chemical dopamine can lead to protein misfolding and neuronal death. Parkinson's Disease is a neurodegenerative disease which results in loss of motor control and cognitive function. Although the cause isn't known precisely, the disease...

2012-05-30 09:57:30

Mutations in the LRRK2 gene are the most common cause of genetic Parkinson's disease (PD). New research published in BioMed Central's open access journal Molecular Neurodegeneration demonstrates that loss of function of LRRK2 (by deletion of the kinase domain) leads to changes in motor co-ordination and causes anxiety-like behaviors and kidney degeneration in mice without affecting dopamine-mediated brain activity. The protein LRRK2 is involved in regulating the structure and function of...

2012-05-16 05:00:22

(Ivanhoe Newswire) — Though there is no known cure for Parkinson´s disease, there are means to control the symptoms. Researchers at UCLA may have found a way to determine which patients will experience a more rapid decline in motor function, which is potentially beneficial in developing new therapies and identifying who can benefit the most from early intervention. In a small study with 233 patients, the researchers discovered that people with Parkinson´s who possess two...

2012-05-16 00:59:30

Two studies by neurological researchers at Rush University Medical Center suggest that, in the future, colonic tissue obtained during either colonoscopy or flexible sigmoidoscopy may be used to predict who will develop Parkinson's disease, a neurodegenerative disorder of aging that that leads to progressive deterioration of motor function due to loss of neurons in the brain that produce dopamine, a neurotransmitter essential to executing movement. Currently, Parkinson's disease afflicts...

2012-04-27 11:28:14

The following research from NewYork-Presbyterian Hospital/ Columbia University Medical Center is being presented at the 64th annual meeting of the American Academy of Neurology (AAN), April 21-26, 2012, in New Orleans. ORAL PRESENTATIONS Dynamic Cerebral Autoregulation Is Transiently Impaired after Large-Vessel Acute Ischemic Stroke Authors: Nils Petersen, Santiago Ortega-Gutierrez, Andres Reccius, Amy Huang, Arjun Masurkar, and Randolph Marshall Background/Significance: Dynamic...

2012-04-18 10:46:54

Suggests way disorder progresses over time in humans Last year, researchers from the Perelman School of Medicine at the University of Pennsylvania found that small amounts of a misfolded brain protein can be taken up by healthy neurons, replicating within them to cause neurodegeneration. The protein, alpha-synuclein (a-syn), is commonly found in the brain, but forms characteristic clumps called Lewy bodies, in neurons of patients with Parkinson's disease (PD) and other neurodegenerative...

2012-04-10 09:08:59

Persistent ocular tremors that prevent eye stability during fixation appear to be common among patients with Parkinson disease (PD) suggesting that precise oculomotor testing could provide an early physiological biomarker for diagnosing PD, according to a report published Online First by Archives of Neurology, a JAMA Network publication. "Although a number of studies describe various oculomotor abnormalities in subjects with PD, conflicts about the specific deficits remain," writes George...


Word of the Day
pungle
  • To take pains; labor assiduously with little progress.
This word comes from the Spanish 'pongale,' put it.
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