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Latest Parkin Stories

2011-12-19 14:57:47

Stabilizing the cell's power-generating center protects against Parkinson's disease (PD) in a rat model, according to a report published online this week in the Journal of Experimental Medicine (www.jem.org). Mitochondria–the energy production center of cells–are damaged in PD, leading to loss of dopaminergic neurons and degeneration of brain function. Taking advantage of the fact that viruses often stabilize mitochondria in order to ensure survival of the cells they infect, a...

2011-12-16 13:59:19

Parkinson's disease is marked by the abnormal accumulation of α-synuclein and the early loss of dopamine neurons in the substantia nigra region of the brain. A polymorphism in the promotor of α-synuclein gene known as NACP-Rep1 has been implicated as a risk factor for the disease. Now, researchers have found that different variants of NACP-Rep1 and its interaction with the microtubule-associated protein tau (MAPT) H1 haplotype can influence the speed of clinical...

2011-12-01 01:47:31

New research in the FASEB Journal suggests that phosphorylated alpha-synuclein, a substance found in the blood of Parkinson's patients, could lead to definitive diagnostic tool A new research report appearing in the December issue of the FASEB Journal (http://www.fasebj.org) shows how scientists from the United Kingdom have developed a simple blood test to detect Parkinson's disease even at the earliest stages. The test is possible because scientists found a substance in the blood, called...

2011-11-30 10:46:46

A University of Kentucky faculty member is a contributing author on a new study demonstrating a connection between a common solvent chemical and Parkinson's disease. Dr. Franca Cambi of the UK Kentucky Neuroscience Institute collaborated with researchers from across the U.S. on a paper recently published in the Annals of Neurology. The novel study looked at a cohort of human twins wherein one twin had been occupationally exposed to trichloroethylene (TCE) and other chemicals believed to be...

2011-11-11 01:20:16

Study of hereditary Parkinson's finds that mitochondria can't be cleared out when damaged Current thinking about Parkinson's disease is that it's a disorder of mitochondria, the energy-producing organelles inside cells, causing neurons in the brain's substantia nigra to die or become impaired. A study from Children's Hospital Boston now shows that genetic mutations causing a hereditary form of Parkinson's disease cause mitochondria to run amok inside the cell, leaving the cell without a...

2011-10-26 00:31:39

The Scripps Research Institute, funded by The Michael J. Fox Foundation, Will Further Investigate the SGK1 Gene — A First Step Toward Developing Possible Treatments for Parkinson´s Disease 23andMe, Inc., a leading personal genetics company, has announced the first-time discovery of the potentially protective nature of the gene serum/glucocorticoid regulated kinase 1 (SGK1) which appears to be protective against a high-risk leucine-rich repeat kinase 2 (LRRK2) mutation for...

2011-10-07 10:27:56

According to new study published in the Journal of Parkinson's Disease In a new study published today in the Journal of Parkinson's Disease, Japanese researchers report that the ability to ride a bike can differentiate between atypical parkinsonism and Parkinson's disease, regardless of the environment or situations for bicycling. Atypical parkinsonisms are disorders that look similar to Parkinson's disease, but respond differently to treatments. The "bicycle sign" can help clinicians...

2011-10-05 19:11:29

New research suggests that small "seed" amounts of diseased brain proteins can be taken up by healthy neurons and propagated within them to cause neurodegeneration. The research, published by Cell Press in the October 6 issue of the journal Neuron, sheds light on the mechanisms associated with Parkinson's disease (PD) and provides a model for discovering early intervention therapeutics that can prevent or slow the devastating loss of neurons that underlies PD. Alpha-synuclein...


Word of the Day
lunula
  • A small crescent-shaped structure or marking, especially the white area at the base of a fingernail that resembles a half-moon.
This word is a diminutive of the Latin 'luna,' moon.
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