Latest PAX3 Stories

New Type of Cancer Discovered By Mayo Clinic Researchers
2014-06-12 08:26:35

Rebekah Eliason for redOrbit.com – Your Universe Online Researchers from Mayo Clinic have recently discovered a new type of cancer. When two perfectly harmless genes, PAX3 and MAML3, abnormally combine during recurring chromosomal mismatch, they can turn dangerous. As the two genes combine, they become a chimera, which is a gene that is made up of half of each. This unique phenomenon causes cancerous biphenotypic sinonasal sarcoma. The tumor usually forms in the nose and continues to...

2011-07-05 13:54:20

Research led by the University of East Anglia has discovered the crucial role of a molecule in skeletal muscle development. The finding could have implications in the future for maintenance of healthy muscle or muscle regeneration in certain diseases, for example cancer and neuromuscular conditions such as muscular dystrophy. The complexity and significance of microRNA molecules has only recently been recognized and they have been implicated in many biological processes, including disease....

2008-12-01 08:59:37

Scientists say they have made a critical discovery in understanding what allows the most aggressive and deadly form of skin cancer to survive and proliferate in the body. Their findings could help doctors design new strategies to prevent malignant melanoma. The process of tanning involves synthesis of the pigment melanin by skin cells called melanocytes, researchers said. That melanin then becomes a natural sunscreen when it spreads to neighboring skin cells, providing some protection against...

2005-09-20 16:01:06

The loss of function of a gene called FOXO1a plays an important role in the development of the most common cancer of soft tissues in children, and restoring the function of that gene in cancer cells suppresses that cancer, according to investigators at St. Jude Children's Research Hospital. The cancer, called alveolar rhabdomyosarcoma (ARMS), arises from immature skeletal muscle cells that remain partially differentiated (do not acquire all the characteristics of a mature muscle cell). The...

Word of the Day
  • The navel or umbilicus.
  • In Greek archaeology: A central boss, as on a shield, a bowl, etc.
  • A sacred stone in the temple of Apollo at Delphi, believed by the Greeks to mark the 'navel' or exact center-point of the earth.
'Omphalos' comes from the ancient Greek.