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Latest PEGylation Stories

2011-06-13 06:30:00

NES-ZIONA, Israel, June 13, 2011 /PRNewswire/ -- PROLOR Biotech, Inc. (NYSE Amex: PBTH), today announced that the U.S. Patent and Trademark Office (PTO) has allowed a new patent for the company's veterinary version of its long-acting CTP-enhanced non-human growth hormone (NhGH-CTP). The patent covers the composition of PROLOR's proprietary pharmaceutical non-human growth hormone as well as certain associated methods of use for veterinary applications. "This new patent covering...

2011-06-06 06:00:00

NES-ZIONA, Israel, June 6, 2011 /PRNewswire/ -- PROLOR Biotech, Inc. (NYSE Amex: PBTH) today reported positive results from a comparative animal study of its long-acting anti-obesity drug candidate oxyntomodulin (OXY-RPEG). The study measured the potential therapeutic effect of OXY-RPEG injected once or twice weekly as measured by weight loss and reduction in food intake compared with oxyntomodulin injected twice daily. It was conducted using a state-of-the-art animal model specifically...

2011-05-31 06:30:00

NES-ZIONA, Israel, May 31, 2011 /PRNewswire/ -- PROLOR Biotech, Inc., (NYSE Amex: PBTH), a clinical stage company developing next generation biobetter therapeutic proteins, today announced that company management will give a corporate presentation at the Jefferies 2011 Global Healthcare Conference on June 6, 2011 at 9:30 AM ET. A live webcast of the company's presentation will be available in the Investors section of PROLOR's website at www.prolor-biotech.com/?CategoryID=215, or at the...

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2011-05-23 14:00:00

Vertex Pharmaceuticals Inc.'s highly anticipated hepatitis C drug has finally won U.S. approval, which will usher in a new marketing battle with a rival medicine from Merck & Co. Incivek is poised to help transform treatment of hepatitis C by nearly doubling the chances of curing the serious liver disease.  Some industry analysts project Incivek sales will top $5 billion a year. The approval was widely expected after an FDA advisory panel unanimously recommended the drug last month....

2011-05-23 06:30:00

NES-ZIONA, Israel, May 23, 2011 /PRNewswire/ -- PROLOR Biotech, Inc. (NYSE Amex: PBTH), a clinical stage company developing next generation biobetter therapeutic proteins, today announced that its proprietary CTP and Reversible PEGylation platforms for extending the longevity of most proteins, peptides and small molecules will be highlighted today in a presentation at the joint meeting of the Summer Neuropeptide Conference and The European Neuropeptide Club (ENC). The joint conference,...

2011-05-20 06:30:00

NES-ZIONA, Israel, May 20, 2011 /PRNewswire/ -- PROLOR Biotech, Inc., (NYSE Amex: PBTH), a clinical stage company developing next generation biobetter therapeutic proteins, today announced that Dr. Abraham Havron, CEO of PROLOR, will give a corporate presentation at the ILSI-Biomed 2011 Conference. The conference will be held at the David InterContinental hotel in Tel Aviv, Israel. The PROLOR corporate presentation is scheduled for May 25, 2011 at 11:20 AM IDT. For more information on...

2011-05-18 07:00:00

NEW YORK and SAN DIEGO, May 18, 2011 /PRNewswire/ -- Ludwig Institute for Cancer Research LTD (LICR) and Polaris Group (Polaris) today announced the formation of a collaboration to expand development of Polaris' novel cancer drug, pegylated arginine deiminase (ADI-PEG 20). ADI-PEG 20 kills tumor cells by depletion of the amino acid arginine. As part of the collaboration, LICR and Polaris will explore further the potential of ADI-PEG 20 as a cancer therapy and aim to identify other amino...

2011-05-12 07:00:00

SAN DIEGO, May 12, 2011 /PRNewswire/ -- Polaris Group (Polaris) today announced that the Company will highlight clinical development plans for its Phase 3-ready pegylated arginine deiminase, ADI-PEG 20, during a symposium held on Tuesday, May 24, at 1:30 p.m. China Standard Time in Taipei, Taiwan. Details about Polaris' upcoming pivotal Phase 3 clinical trial of ADI-PEG 20 in hepatocellular carcinoma (HCC) will be presented by the principal investigator, Ghassan Abou-Alfa, M.D., of...

2011-04-18 08:00:00

- No Interruption in Production for Key Drug Used to Treat Acute Lymphoblastic Leukemia - GAITHERSBURG, Md., April 18, 2011 /PRNewswire/ -- Sigma-Tau Pharmaceuticals, Inc. is pleased to announce that it has received approval from the U.S. Food and Drug Administration (FDA) to manufacture L-asparaginase, the primary ingredient in the oncology medicine ONCASPAR® (pegaspargase). ONCASPAR is the only FDA-approved PEGylated formulation of L-asparaginase which is a key...

2011-04-11 09:13:00

SAN DIEGO, April 11, 2011 /PRNewswire/ -- Polaris Group (Polaris) announced today that data from preclinical studies of ADI-PEG 20, the Company's pegylated arginine deiminase therapeutic, is synergistic with hydroxychloroquine (ChQ) in a human pancreatic cancer cell line and with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in human melanoma cell lines. Both ChQ and TRAIL are known inhibitors of autophagy. These results support the commencement of Phase 1/2 clinical...


Word of the Day
negawatt
  • A unit of saved energy.
Coined by Amory Lovins, chairman of the Rocky Mountain Institute as a contraction of negative watt on the model of similar compounds like megawatt.