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Latest Perforin Stories

2011-06-09 23:36:54

After eight years of work, researchers have unearthed what has been a well-kept secret of our immune system's success. The findings published online on June 9th in Immunity, a Cell Press publication, offer an explanation for how specialized immune cells are able to kill infected or cancerous cells without killing themselves in the process. The focus of the study is a molecule known as perforin, whose job it is to open up a pore in cells targeted for destruction. With that pore in place,...

2010-11-01 15:24:58

Assassin's tricks revealed in Nature today A team of Melbourne and London researchers have shown how a protein called perforin punches holes in, and kills, rogue cells in our bodies. Their discovery of the mechanism of this assassin is published today in the science journal Nature. "Perforin is our body's weapon of cleansing and death," says project leader Prof James Whisstock from Monash University. "It breaks into cells that have been hijacked by viruses or turned into cancer cells and...

2010-11-01 15:22:35

Scientists from the UK and Australia have seen the human immune system's assassin "“ a protein called perforin "“ in action for the first time. The UK team, funded by the Biotechnology and Biological Sciences Research Council (BBSRC) and the Wellcome Trust, is based at Birkbeck College where they used powerful electron microscopes to study the mechanism that perforin uses to punch holes in rogue cells. The research is published today (1800hrs, 31 October) in Nature. Professor...


Word of the Day
omadhaun
  • A fool; a simpleton: a term of abuse common in Ireland and to a less extent in the Gaelic-speaking parts of Scotland.
This word is partly Irish in origin.