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Latest Pericyte Stories

2014-07-09 11:17:04

NIH/National Institute of Neurological Disorders and Stroke NIH-funded researchers find brain tumor cells disrupt the brain's protective barrier, offering potential avenues for therapy Invading glioblastoma cells may hijack cerebral blood vessels during early stages of disease progression and damage the brain's protective barrier, a study in mice indicates. This finding could ultimately lead to new ways to bring about the death of the tumor, as therapies may be able to reach these...

2014-05-27 15:47:27

Lund University Two years ago, a new type of stem cell was discovered in the brain that has the capacity to form new cells. The same research group at Lund University in Sweden has now revealed that these stem cells, which are located in the outer blood vessel wall, appear to be involved in the brain reaction following a stroke. The findings show that the cells, known as pericytes, drop out from the blood vessel, proliferate and migrate to the damaged brain area where they are converted...

2014-03-26 16:19:50

Long-term brain damage caused by stroke could be reduced by saving cells called pericytes that control blood flow in capillaries Long-term brain damage caused by stroke could be reduced by saving cells called pericytes that control blood flow in capillaries, reports a new study led by scientists from UCL (University College London). Until now, many scientists believed that blood flow within the brain was solely controlled by changes in the diameter of arterioles, blood vessels that...

Study Suggests Brain Blood Vessel Cells May Be Therapeutic Targets For Alzheimer's Disease
2013-12-13 14:28:51

NIH/National Institute of Neurological Disorders and Stroke A study in mice shows how a breakdown of the brain's blood vessels may amplify or cause problems associated with Alzheimer's disease. The results published in Nature Communications suggest that blood vessel cells called pericytes may provide novel targets for treatments and diagnoses. "This study helps show how the brain's vascular system may contribute to the development of Alzheimer's disease," said study leader Berislav V....

2013-04-30 23:29:14

Many diseases — obesity, Type 2 diabetes, muscular dystrophy — are associated with fat accumulation in muscle. In essence, fat replacement causes the muscles to weaken and degenerate. Scientists at Wake Forest Baptist Medical Center have discovered the biological mechanism involved in this process, which could point the way to potential therapies. The findings are published in the April 27 online edition of Stem Cells and Development. The Wake Forest Baptist researchers...

How Blood Vessels Regroup After Stroke
2013-02-11 10:53:18

Rice University [ Watch The Video ] By thinking of cells as programmable robots, researchers at Rice University hope to someday direct how they grow into the tiny blood vessels that feed the brain and help people regain functions lost to stroke and disease. Rice bioengineer Amina Qutub and her colleagues simulate patterns of microvasculature cell growth and compare the results with real networks grown in their lab. Eventually, they want to develop the ability to control the way...

New Blood-vessel-generating Cell With Therapeutic Potential Discovered
2012-10-17 10:39:06

Researchers at the University of Helsinki, Finland, believe they have discovered stem cells that play a decisive role in new blood vessel growth. If researchers learn to isolate and efficiently produce these stem cells found in blood vessel walls, the cells offer new opportunities in the treatment of cardiovascular diseases, cancer and many other diseases. The study will be published in the PLOS Biology journal on 16 October 2012. The growth of new blood vessels, also known as...

Neurons Produced Via Adult Cells
2012-10-05 10:15:06

[ Watch the Video: New Human Neurons from Adult Cells Right There in the Brain ] Connie K. Ho for redOrbit.com — Your Universe Online Difficulties in balance and movement, hesitation in breathing and talking are just a few of the detrimental effects of neurodegenerative disease, and the illness can sometimes be serious or even life threatening. In the research community, more studies are being done to understand how these disorders can be treated. In particular, a new study...

2012-09-04 11:52:43

New insights on cardiac pathology reported in the American Journal of Pathology Cardiac injury leads to significant structural changes in the heart, including enlargement, excess formation of fibrous growth tissue, and abnormalities of the coronary vasculature. While associated factors have been targeted for therapeutic intervention, the results have been conflicting. Most studies have investigated these changes after six days of injury. However, advanced stages of remodeling have already...

2012-01-18 06:29:54

(Ivanhoe Newswire) — A new study found that a group of little-explored cells in the tumor microenvironment can likely serve as gatekeepers against cancer progression and metastasis. One known way of treating cancer is by targeting angiogenesis, or blood vessel growth. Raghu Kalluri, MD, PhD, Chief of the Division of Matrix Biology at Beth Israel Deaconess Medical Center (BIDMC) and Professor of Medicine at Harvard Medical School (HMS) and colleagues, hypothesized whether targeting a...


Word of the Day
tessitura
  • The prevailing range of a vocal or instrumental part, within which most of the tones lie.
This word is Italian in origin and comes from the Latin 'textura,' web, structure.