Latest Pericyte Stories

2012-01-18 00:07:26

Paradoxical discovery finds that a group of cells known as pericytes help prevent metastasis A new study finds that a group of little-explored cells in the tumor microenvironment likely serve as important gatekeepers against cancer progression and metastasis. Published in the January 17 issue of Cancer Cell, these findings suggest that anti-angiogenic therapies — which shrink cancer by cutting off tumors' blood supply — may inadvertently be making tumors more aggressive and...

2011-12-02 01:37:00

Tracking individual cells within the lungs as they move around and multiply has given Duke University researchers new insights into the causes of Idiopathic Pulmonary Fibrosis (IPF) a disease which can only be treated now by lung transplantation. IPF fills the delicate gas exchange region of the lung with scar tissue, progressively restricting breathing. The Duke University Medical Center researchers have discovered that some commonly held ideas about the origins of the scar-forming...

2010-10-14 13:36:40

While the blood-brain barrier (BBB) protects the brain from harmful chemicals occurring naturally in the blood, it also obstructs the transport of drugs to the brain. In an article in Nature scientists at the Swedish medical university Karolinska Institutet now present a potential solution to the problem. The key to the BBB is a cell-type in the blood vessel walls called pericytes, and the researchers hope that their findings will one day contribute to new therapies for diseases like...

2008-09-23 00:00:29

The walls of blood vessels contain adult stem cells with the unlimited potential to differentiate into human tissues such as bone, cartilage and muscle, Children's Hospital of Pittsburgh announced today. The cells, known as pericytes, are described by Children's researchers in this month's issue of the journal Cell Stem Cell. "This finding marks the first direct evidence of the source of multipotent adult stem cells known as mesenchymal stem cells. We believe pericytes represent one of the...

2008-09-22 15:00:53

U.S. medical scientists said they have identified a source of adult stem cells on the walls of blood vessels. Researchers at the Children's Hospital of Pittsburgh said the newly identified adult stem cells have the unlimited potential to differentiate into human tissues such as bone, cartilage and muscle. The scientists, led by Bruno Peault, deputy director of the Stem Cell Research Center at the hospital, identified cells known as pericytes, which have broad developmental potential. The...

2005-08-01 19:28:17

A gene better known for its role in preventing cancer also plays a key role in the developing embryo, where the gene prevents excessive growth of blood vessels, according to investigators at St. Jude Children's Research Hospital. The gene, called Arf, prevents the accumulation of certain cells, called pericytes, that nurture the growth of blood vessels in the eye during embryonic development, the researchers said. This observation is of interest because Arf also works with a gene called p53...

Word of the Day
  • A gigantic fictional humanoid alien god being described with a head resembling an octopus and dragon wings and claws, around whom an insane cult developed.
  • Pertaining to the mythos of Cthulhu and additional otherworldly beings created by H. P. Lovecraft or inspired by his writings and imitators.
This word was invented in 1926 by H.P. Lovecraft for his short story, 'The Call of Cthulhu.' 'Cthulhu' may be based on the word 'chthonic,' which in Greek mythology refers to the underworld.