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Latest Peripheral membrane proteins Stories

2009-12-28 16:59:32

FINDINGS: Several structurally similar small molecules appear capable of protecting cells from alpha-synuclein toxicity, a hallmark of Parkinson's disease. RELEVANCE: Parkinson's disease is a neurodegenerative disorder characterized by tremors, muscle rigidity, and slowed movements. There is currently no cure for the disease, and current Parkinson's therapies only address disease symptoms, not the disease's cellular cause. Small molecules found to protect cells in multiple models of...

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2009-12-23 07:06:16

Communication between nerve cells is vital for our bodies to function. Part of this communication happens through vesicles containing signaling molecules called neurotransmitters. The vesicle fuses with the nerve cell membrane; the neurotransmitters are released and quickly recorded by the next nerve cell. It is crucial that new vesicles constantly are produced for the nerve cell communication continuously to take place. If parts of this communication do not work, it leads to nerve pain like...

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2009-12-18 08:42:57

Scientists at Washington University have isolated a channel that shuttles the vital but vulnerable heme molecule across biological membranes In some ways a cell in your body or an organelle in that cell is like an ancient walled town. Life inside either depends critically on the intelligence of the gatekeepers. If too many barbarians sneak into town, the town may be put to the torch. And if the cellular gatekeepers can't control the flow of ions and molecules into and out of the cell, the...

2009-12-15 13:00:00

NEW YORK, Dec. 15 /PRNewswire-USNewswire/ -- The Michael J. Fox Foundation announced $1.7 million in funding to drive new and continuing Parkinson's research projects at the Banner Sun Health Research Institute and Mayo Clinic Arizona, sites of the Arizona Parkinson's Disease Consortium. Of the total funding, $1.1 million represents renewed funding for directed projects led by principal investigators Charles Adler, MD, PhD, at Mayo Clinic Arizona and Thomas Beach, MD, PhD, at Banner Sun...

2009-10-18 12:05:14

New research clarifies how neurotransmitters like norepinephrine, serotonin, and dopamine, are regulated "“ a finding that may help fine-tune therapies for depression. Current drugs for depression target the regulatory process for neurotransmitters, and while effective in some cases, do not appear to work in other cases. Recent findings suggest that synucleins, a family of small proteins in the brain, are key players in the management of neurotransmitters -- specifically, alpha- and...

2009-10-16 10:35:48

A series of studies have demonstrated that Chrysanthemum indicum possesses antimicrobial, antiinflammatory, immunomodulatory, and neuroprotective effects. Recently, much attention has been devoted to the anticancer activity of Chrysanthemum indicum, especially in hepatocellular carcinoma (HCC). However, its anticancer mechanism of action is still not clear and needs further investigation. A research article to be published on September 28, 2009 in the World Journal of Gastroenterology...

2009-10-14 05:00:00

STOCKHOLM, October 14 /PRNewswire/ -- Athera Biotechnologies AB, an atherosclerosis R&D company developing novel products for treatment and prevention of cardiovascular disease (CVD), announced today that the European Patent Office intends to grant two key patents related to the Company's intellectual property on its two pharmaceutical candidates Annexin A5 and PC-mAb. Following subsequent grant the patents will be registered in the designated European countries, and there are...

2009-10-13 10:47:19

Both genetic and pathologic data indicate a role for the neuronal protein alpha-synuclein in Parkinson disease. Previous studies have indicated that phosphorylation of alpha-synuclein at amino acid 129 (Ser129) is a key event in alpha-synuclein"“mediated nerve cell toxicity. However, Mel Feany and colleagues, at Brigham and Women's Hospital, Boston, have now identified a counterbalancing role in nerve cell protection for phosphorylation of alpha-synuclein amino acid 125 (Tyr125). In the...

2009-10-08 09:35:27

The natural cycle of building bone to maintain skeletal strength and then breaking it down for the body's calcium needs is delicately balanced, but diseases like osteoporosis break down too much bone without adequate bone replacement, leading to bone fractures. The results from a new study at Duke suggest a targeted approach by which drugs may be able to fight osteoporosis and other degenerative bone diseases. Diane Gesty-Palmer, M.D., a Duke Assistant Professor of Endocrinology and...

2009-09-21 11:01:00

VIENNA, Austria, September 21 /PRNewswire/ -- EUCODIS Bioscience, a company developing, customizing, manufacturing, and marketing enzymes for the chemical industry, announced today that it has launched the first enzymes of its lipase portfolio. EUCODIS Bioscience currently offers 12 lipases that have been selected to cover a broad range of potential industrial applications. Lipases are an enzyme family that is widely used across the chemical industry, including the pharmaceutical,...


Latest Peripheral membrane proteins Reference Libraries

Paneth Cells
2012-07-01 19:03:07

Paneth Cells are one of four principal cell types found in the epithelium of the small intestine; the other three are the goblet cell, enterocyte, and enteroendocrine cell. Paneth cells may also be found in the cecum and appendix, although sporadically. These cells are identifiable microscopically by their location just below the intestinal stem cells in the intestinal glands. and the large eosinophilic refractile granules that occupy most of their cytoplasm. These granules consist of...

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