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Latest Peripheral membrane proteins Stories

2014-02-18 14:09:05

Researchers from Warwick Medical School have discovered the key role of a protein in shutting down endocytosis during mitosis, answering a question that has evaded scientists for half a century. The study, published today in the journal eLife, is the first to outline the role of actin, a protein, in shutting down clathrin-dependent endocytosis during mitosis. Endocytosis is the process by which cells absorb molecules that are too large to pass through the plasma membrane, such as...

2014-01-15 14:29:54

Recent highlights in Molecular Biology and Evolution Defensins, as their name implies, are small proteins found in plants and animals that help ward off viral, bacterial or fungal pests. One fascinating question of invertebrate evolution is how these proteins evolved into venoms to attack their prey. Based on structural similarity, it was proposed that scorpion toxins and antimicrobial invertebrate defensins could have a common ancestor. To address how a nontoxic protein develops into a...

2014-01-08 17:05:18

Gladstone findings challenge conventional wisdom; point to new therapeutic strategies The most devastating aspect of Parkinson's disease may not be its debilitating symptoms, which rob its victims of their ability to control their own movement. It may not be the millions around the world and their families who suffer each day from the disease's harmful effects. Instead, it may in fact be that its root causes remain largely a mystery. But now, scientists at the Gladstone Institutes have...

2013-11-01 10:40:00

The ever-increasing threat from "superbugs" -- strains of pathogenic bacteria that are impervious to the antibiotics that subdued their predecessor generations -- has forced the medical community to look for bactericidal weapons outside the realm of traditional drugs. One promising candidate is the antimicrobial peptide (AMP), one of Mother Nature's lesser-known defenses against infections, that kills a pathogen by creating, then expanding, nanometer-sized pores in the cell membrane until it...

2013-10-18 11:24:28

Leishmaniasis is a vector borne disease caused by different Leishmania species with different clinical manifestations. Cutaneous leishmaniasis (CL) is endemic and widespread especially among young individuals in Iran. Currently prophylactic or therapeutic vaccines are not available, and in spite of vector control wherever possible, the disease has not been controlled. Although the majority of zoonotic CL cases heal within 6-9 months, anthroponotic cases persist much longer. Both types leave...

2013-09-24 23:27:47

Global Hemophilia Market Report: 2013 Edition research studies the hemophilia market on a global scale and its various segments. Dallas, Texas (PRWEB) September 24, 2013 The key trends observed within the global hemophilia market include inclination towards prophylaxis, long-acting factor VIII and IX development and growing penetration of rFVIII products in emerging markets which is a opportunity for manufacturers. On the development front, there has been an increase in the launch of new...

2013-09-23 14:00:33

Eukaryotic cells are compartmentalized by membranes, whose shape and dynamics are precisely regulated to maintain their correct functions. Consequently, many cellular processes such as endocytosis, migration and morphogenesis rely on proteins that bind directly to membranes and sculpt them into desired shapes. BAR domain proteins are among the central membrane-sculpting proteins in all eukaryote cells. Studies by Pekka Lappalainen laboratory at Institute of Biotechnology, University of...

Biophysicists Zoom In On Pore-forming Toxin
2013-08-15 09:08:14

Rice University Study of melittin-based pore formation also applies to anticancer drugs A new study by Rice University biophysicists offers the most comprehensive picture yet of the molecular-level action of melittin, the principal toxin in bee venom. The research could aid in the development of new drugs that use a similar mechanism as melittin's to attack cancer and bacteria. The study appears this week in the Proceedings of the National Academy of Sciences. Melittin does its...


Latest Peripheral membrane proteins Reference Libraries

Paneth Cells
2012-07-01 19:03:07

Paneth Cells are one of four principal cell types found in the epithelium of the small intestine; the other three are the goblet cell, enterocyte, and enteroendocrine cell. Paneth cells may also be found in the cecum and appendix, although sporadically. These cells are identifiable microscopically by their location just below the intestinal stem cells in the intestinal glands. and the large eosinophilic refractile granules that occupy most of their cytoplasm. These granules consist of...

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Word of the Day
callithump
  • A somewhat riotous parade, accompanied with the blowing of tin horns, and other discordant noises; also, a burlesque serenade; a charivari.
'Callithump' is a back-formation of 'callithumpian,' a 'fanciful formation' according to the Oxford English Dictionary. However, the English Dialect Dictionary, says 'Gallithumpians' is a Dorset and Devon word from the 1790s that refers to 'a society of radical social reformers' or 'noisy disturbers of elections and meetings.'
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