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Latest Peripheral membrane proteins Stories

2012-04-18 10:46:54

Suggests way disorder progresses over time in humans Last year, researchers from the Perelman School of Medicine at the University of Pennsylvania found that small amounts of a misfolded brain protein can be taken up by healthy neurons, replicating within them to cause neurodegeneration. The protein, alpha-synuclein (a-syn), is commonly found in the brain, but forms characteristic clumps called Lewy bodies, in neurons of patients with Parkinson's disease (PD) and other neurodegenerative...

2012-04-16 23:29:44

Injection of a small amount of clumped protein triggers a cascade of events leading to a Parkinson's-like disease in mice, according to an article published online this week in the Journal of Experimental Medicine. Progressive accumulation of clumps of the protein alpha-synuclein in the brains of patients with Parkinson's disease coincides with the onset of motor dysfunction. However, whether these clumps are sufficient to trigger neurodegeneration, and how these clumps spread throughout...

2012-04-04 20:29:44

Researchers study special forms of a conotoxin that blocks transmission of pain signals Hidden in the mud, the cone snail Conus purpurascens lies in wait for its victims. It attracts its prey, fish, with its proboscis, which can move like a worm, protruding from the mud. Once a fish approaches out of curiosity, the snail will rapidly shoot a harpoon at it, which consists of an evolutionarily modified tooth. The paralyzed victim then becomes an easy meal. It takes the venomous cone snail...

2012-03-20 23:42:19

Curcumin, a compound found in the spice turmeric, is proving effective at preventing clumping of a protein involved in Parkinson´s disease, says a Michigan State University researcher. A team of researchers led by Basir Ahmad, an MSU postdoctoral researcher, demonstrated earlier this year that slow-wriggling alpha-synuclein proteins are the cause of clumping, or aggregation, which is the first step of diseases such as Parkinson´s. A new study led by Ahmad, which appears in the...

2012-03-19 19:23:27

Food-borne diseases might soon have another warrior to contend with, thanks to a new molecule discovered by chemists at the University of Illinois. The new antibiotic, an analog of the widely used food preservative nisin, also has potential to be a boon to the dairy industry as a treatment for bovine mastitis. The antibiotic nisin occurs naturally in milk, a product of bacteria resident in the cow's udder. It helps keep milk from spoiling and kills a broad spectrum of bacteria that cause...

2012-03-02 13:44:32

Molecular 'tweezers' break up toxic aggregations of proteins Millions of people suffer from Parkinson's disease, a disorder of the nervous system that affects movement and worsens over time. As the world's population ages, it's estimated that the number of people with the disease will rise sharply. Yet despite several effective therapies that treat Parkinson's symptoms, nothing slows its progression. While it's not known what exactly causes the disease, evidence points to one particular...

2012-02-23 19:00:00

Sanford-Burnham researchers determine the first 3D structure of the botulinum neurotoxin, together with the protein bodyguard that guides it through the body–revealing weak spots that could be exploited to develop new counterterrorism measures. La Jolla, Calif. (PRWEB) February 23, 2012 Researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) and the Medical School of Hannover in Germany recently discovered how the botulinum neurotoxin, a potential bioterrorism...


Latest Peripheral membrane proteins Reference Libraries

Paneth Cells
2012-07-01 19:03:07

Paneth Cells are one of four principal cell types found in the epithelium of the small intestine; the other three are the goblet cell, enterocyte, and enteroendocrine cell. Paneth cells may also be found in the cecum and appendix, although sporadically. These cells are identifiable microscopically by their location just below the intestinal stem cells in the intestinal glands. and the large eosinophilic refractile granules that occupy most of their cytoplasm. These granules consist of...

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Word of the Day
glogg
  • Scandinavian punch made of claret and aquavit with spices and raisins and orange peel and sugar.
This word comes from the Swedish 'glogg,' which is an alteration of 'glodgat,' mulled (wine).
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