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Latest Peroxisome proliferator-activated receptor Stories

2014-05-29 04:21:56

AHMEDABAD, India, May 29, 2014 /PRNewswire/ -- Commences Phase III trials of Lipaglyn(TM) (Saroglitazar) in patients suffering from Lipodystrophy Exploring newer therapeutic usage of its breakthrough drug Lipaglyn(TM) (Saroglitazar), the Zydus Group has now initiated Phase III trials of the molecule for patients suffering from lipodystrophy. The drug is already approved in India for treating diabetic dyslipidemia and hypertriglyceridemia. The goal of this trial is to...

2013-04-23 22:38:17

Epoxide hydrolase inhibition and thiazolidinediones Scientists at the Medical College of Wisconsin and the University of California at Davis, led by Dr. John Imig and Dr. Bruce Hammock have determined the synergistic actions of inhibiting soluble epoxide hydrolase (sEH) with tAUCB (trans-4-(4-[3-adamantan-1-yl-ureid]-cyclohexyloxy)-benzoic acid) and activating peroxisome proliferator-activator receptorγ (PPARγ) with the thiazolidinedione rosiglitazone on the...

Obesity Study Looks At Brown Fat Cells
2013-03-15 06:11:35

Enid Burns for redOrbit.com — Your Universe Online Many of us don't know the difference between brown fat cells and white fat cells. But researchers at Perelman School of Medicine at the University of Pennsylvania, led by Patrick Seale, Ph.D., are looking at brown fat cells to better understand how they develop. The researchers believe that the brown fat cell makes heat for the body, which has helped mammals cope with the cold. New theories say the warmth generated in brown fat...

2012-10-09 22:19:00

Discovery of new biological pathway may help scientists redesign certain diabetes drugs to eliminate or reduce adverse side effects Many drugs work by "fixing" a particular biological pathway that's gone awry in a disease. But sometimes drugs affect other pathways too, producing undesirable side effects that can be severe enough to outweigh the drug's benefits. Such is the case for the thiazolidinedione drugs (also known as TZDs), which are used to treat type 2 diabetes. These are...

A New Target For The Treatment Of Diabetes And Obesity
2012-08-02 15:15:52

Researchers at Washington University School of Medicine in St. Louis have identified a potential target for treating diabetes and obesity. Studying mice, they found that when the target protein was disabled, the animals became more sensitive to insulin and were less likely to get fat even when they ate a high-fat diet that caused their littermates to become obese. The findings are published online in the journal Cell Metabolism. The researchers studied how the body manufactures fat...

2012-01-18 15:11:58

New Findings Could Influence Design of Future Diabetes Treatments Using a blend of technologies, scientists from the Florida campus of The Scripps Research Institute have painted a new picture of how biochemical information can be transmitted through the modification of a protein. Previously, scientists believed that during the pairing of proteins and their binding partners (“ligands”), proteins modified their shape while ligands remained stable. The new study shows this...

2012-01-10 23:40:04

New findings could influence design of future diabetes treatments Using a blend of technologies, scientists from the Florida campus of The Scripps Research Institute have painted a new picture of how biochemical information can be transmitted through the modification of a protein. Previously, scientists believed that during the pairing of proteins and their binding partners ("ligands"), proteins modified their shape while ligands remained stable. The new study shows this one-size-fits-all...

Study May Lead To Better, Safer Drug For Diabetes
2011-11-22 05:05:26

Study reveals a natural fatty acid used in manufacturing can modulate glucose control A Van Andel Research Institute (VARI) study published recently in the Journal of Biological Chemistry reveals that a natural fatty acid can serve as a regulator of blood sugar levels, which may have important applications in designing better and safer drugs for diabetes treatment. According to the U.S. Center for Disease Control and Prevention (CDC), nearly 26 million Americans have diabetes, and...


Word of the Day
grass-comber
  • A landsman who is making his first voyage at sea; a novice who enters naval service from rural life.
According to the OED, a grass-comber is also 'a sailor's term for one who has been a farm-labourer.'