Latest Peter Coveney Stories
The combined supercomputing power of the UK and US â€˜national gridsâ€™ has enabled UCL (University College London) scientists to simulate the efficacy of an HIV drug in blocking a key protein used by the lethal virus. The method â€“ an early example of the Virtual Physiological Human in action â€“ could one day be used to tailor personal drug treatments, for example for HIV patients developing resistance to their drugs.
Large-scale computer simulations have pinpointed a tiny change in molecular structure that could account for drug resistance in Streptomices pneumoniae, the organism that causes childhood pneumonia and claims 3.5 million lives a year, mainly in developing countries. Such knowledge could be invaluable in designing new drugs that are effective against the drug resistant strain.
- Monstrous in size or character; huge; prodigious; monstrously perverse, savage, cruel, etc.