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Last updated on April 20, 2014 at 17:20 EDT

Latest Peter Reddien Stories

2012-03-02 13:06:04

FINDINGS: Devising a novel method to identify potential genetic regulators in planarian stem cells, Whitehead Institute scientists have determined which of those genes affect the two main functions of stem cells. Three of the genes are particularly intriguing because they code for proteins similar to those known to regulate mammalian embryonic stem cells. Such genetic similarity makes planarians an even more attractive model for studying stem cell biology in vivo. RELEVANCE: Stem cells may...

2011-05-16 19:24:39

Worm with abundant ability to regenerate relies on ancient gene to make decisions Most people don't think worms are cool. But the tiny flatworm that Northwestern University scientist Christian Petersen studies can do something very cool indeed: it can regenerate itself from nearly every imaginable injury, including decapitation. When cut in half, it becomes two worms. This amazing ability of the planarian flatworm to regenerate its entire body from a small wedge of tissue has fascinated...

2011-05-12 22:18:51

A seldom-studied gene known as notum plays a key role in the planarian's regeneration decision-making process, according to Whitehead Institute scientists. Protein from this gene determines whether a head or tail will regrow at appropriate amputation sites. Since the late 1800s, scientists have been fascinated by the planarian's amazing ability to regenerate its entire body from a small wedge of tissue. Whitehead Member Peter Reddien and former postdoctoral fellow Christian Petersen recently...

2011-05-12 22:15:50

A single adult cell from one of the most impressive masters of regeneration in the animal kingdom "“ the planarian "“ is all it takes to build a completely functional new worm, researchers have learned. The study provides the first hard evidence that adult planarians harbor pluripotent stem cells "“ cells capable of producing the diverse range of tissue types necessary to build a complete animal. Distributed throughout the worm body, the newfound cells appear to have the...

2009-09-14 15:37:11

Amputations trigger a molecular response that determines if a head or tail will be regrown in planaria, a flatworm commonly studied for its regenerative capabilities. Until now, no molecular connection between wounding and the decision to regenerate either a head or tail in planaria had been identified. Whitehead Institute scientists report this finding in the September 15-28 issue of PNAS Early Edition. Regeneration is the regrowth of part of an organism's body after it has been damaged or...