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Latest PGC Stories

Clearer Way To Treat Huntington's Disease Offered By 2 Proteins
2012-07-11 20:58:47

Pair helps remove and prevent misfolding of proteins that cause neurodegeneration In a paper published in the July 11 online issue of Science Translational Medicine, researchers at the University of California, San Diego School of Medicine have identified two key regulatory proteins critical to clearing away misfolded proteins that accumulate and cause the progressive, deadly neurodegeneration of Huntington's disease (HD). The findings explain a fundamental aspect of how HD wreaks havoc...

2009-03-04 11:21:05

A U.S. study in mice sheds light on the insulin resistance that can come from diets loaded with high-fructose corn syrup, researchers said. The study, published in the journal Cell Metabolism, showed that mice on a high-fructose diet were protected from insulin resistance when a gene known as transcriptional coactivator PPARg coactivator-1b -- PGC-1b -- was knocked down in the animals' liver and fat tissue. PGC-1b coactivates a number of transcription factors that control the activity of...

2009-03-04 07:49:37

A new study in mice sheds light on the insulin resistance that can come from diets loaded with high-fructose corn syrup, a sweetener found in most sodas and many other processed foods. The report in the March issue of Cell Metabolism, a Cell Press publication, also suggests a way to prevent those ill effects.The researchers showed that mice on a high-fructose diet were protected from insulin resistance when a gene known as transcriptional coactivator PPARg coactivator-1b (PGC-1b) was "knocked...


Word of the Day
sough
  • A murmuring sound; a rushing or whistling sound, like that of the wind; a deep sigh.
  • A gentle breeze; a waft; a breath.
  • Any rumor that engages general attention.
  • A cant or whining mode of speaking, especially in preaching or praying; the chant or recitative characteristic of the old Presbyterians in Scotland.
  • To make a rushing, whistling, or sighing sound; emit a hollow murmur; murmur or sigh like the wind.
  • To breathe in or as in sleep.
  • To utter in a whining or monotonous tone.
According to the OED, from the 16th century, this word is 'almost exclusively Scots and northern dialect until adopted in general literary use in the 19th.'
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