Quantcast

Latest Phagocytes Stories

2010-12-02 00:44:46

For the first time, scientists have described not only the identities and quantities of fat species in a living mammalian cell "“ in this case, a mouse macrophage or white blood cell "“ but they also report how these lipids react and change over time to a bacterial stimulus triggering the cell's immune response. Writing in the December 17 issue of the Journal of Biological Chemistry, lead author Edward A. Dennis, PhD, distinguished professor of pharmacology, chemistry and...

2010-10-25 16:17:36

A new study reveals that two enzymes help immune cells deploy pathogen-killing traps by unraveling and using the chromatin (DNA and its associated proteins) contained in the cells' nuclei to form defensive webs. The study appears online on October 25 in The Journal of Cell Biology (www.jcb.org). Neutrophils, the most common type of white blood cells, are difficult to study because they live for only about six hours. So Arturo Zychlinsky and colleagues, from the Max Planck Institute for...

2010-10-15 17:09:01

research published in Science Researchers at the University of Calgary Faculty of Medicine are using an innovative new imaging technique to study how white blood cells (called neutrophils) respond to inflammation, and have revealed new targets to inhibit the response. When the body is invaded by infection, the immune system counters by generating inflammation with deployment of white blood cells to the site of danger to kill invading bacteria. However, inappropriate inflammation occurs in the...

2010-07-29 15:28:20

Researcher discovers existing drugs can potentially target the disease's ability to spread Often causing no symptoms in carriers of the disease, worldwide tuberculosis (TB) infects eight to ten million people every year, kills two million, and it is highly contagious as it is spread through coughing and sneezing. "It's a global health disaster waiting to happen, even here in Canada, but this new paradigm in TB research may offer an immediate opportunity to improve vaccination and treatment...

edb9bc436d456e171b0e3b1493129e98
2009-12-11 09:17:44

Finding how to block the pathway may lead to new therapies for TB and other disorders Scientists have discovered a signaling pathway that tuberculosis bacteria use to coerce disease-fighting cells to switch allegiance and work on their behalf. Epithelial cells line the airways and other surfaces to protect and defend the body. Tuberculosis bacteria co-opt these epithelial cells into helping create tubercles: the small, rounded masses characteristic of TB. The tubercles enable the bacteria to...

2009-11-03 12:29:08

University of Illinois at Chicago College of Medicine researchers have identified the important role a protein plays in the body's first line of defense in directing immune cells called neutrophils toward the site of infection or injury. Their results are described online in the Proceedings of the National Academy of Sciences. Neutrophils are white blood cells that are activated by chemical cues to move quickly to the site of injury or infection, where they ingest bacteria. When alerted to...

2009-10-21 04:00:00

LAS VEGAS, Oct. 21 /PRNewswire/ -- Using live blood cell analysis, a resveratrol-based nutriceutical (Longevinex®) has been shown to visibly activate sluggish white blood cells in 9 of 10 human subjects within 30 minutes of consumption. To view the Multimedia News Release, go to: http://multivu.prnewswire.com/mnr/longevinex/40599/ (Photo: http://www.newscom.com/cgi-bin/prnh/20091021/NY96112 ) "This demonstration should allay poorly-founded concerns that resveratrol...

625c61a2e8e6767063464e6d6168d8431
2009-09-22 09:46:23

For scientists at the European Molecular Biology Laboratory (EMBL) in Monterotondo, Italy, what seemed like a disappointing result turned out to be an important discovery. Their findings, published online this week in the journal Proceedings of the National Academy of Sciences (PNAS), provide conclusive proof that, when a muscle is injured, white blood cells called macrophages play a crucial role in its regeneration. The scientists also uncovered the genetic switch that controls this process,...

2009-04-28 11:23:10

 For decades, microbiologists assumed that macrophages, immune cells that can engulf and poison bacteria and other pathogens, killed microbes by damaging their DNA. A new study from the University of Illinois disproves that.The study, published in the journal PLoS ONE, shows that macrophages focus their most potent poisons, known as reactive oxygen species (ROS), on targets outside the cytoplasm.Macrophages are voracious eaters that "swallow" cellular debris and invading organisms. They...

2005-07-01 15:45:00

Scientists at UCSD have determined how white blood cells up the ante against invading bacteria, a finding that may lead to new treatments for infections including those caused by invasive"”"flesh-eating""” Streptococcus bacteria. The findings, which are published in the July, 2005 issue of The Journal of Clinical Investigation, represent a collaborative effort between the laboratories of Randall Johnson, UCSD professor of biology and Victor Nizet, associate professor of pediatrics...


Word of the Day
monteith
  • A large punch-bowl of the eighteenth century, usually of silver and with a movable rim, and decorated with flutings and a scalloped edge. It was also used for cooling and carrying wine-glasses.
  • A kind of cotton handkerchief having white spots on a colored ground, the spots being produced by a chemical which discharges the color.
This word is possibly named after Monteith (Monteigh), 'an eccentric 17th-century Scotsman who wore a cloak scalloped at the hem.'
Related