Latest phenytoin Stories
Phenytoin is a well known antiepileptic agent widely used throughout the world. Recent clinical studies in patients with bipolar disorder have suggested that, as for other anticonvulsant drugs commonly used in the treatment of bipolar patients including valproate and carbamazepine, phenytoin may have mood-stabilizing effects in addition to its well-known anticonvulsant properties. In a study published in the March 2010 issue of Experimental Biology and Medicine Veronica Mariotti and...
ATLANTA, March 11 /PRNewswire/ -- UCB today announced that the antiepileptic drug (AED) Vimpat® (lacosamide) (C-V) demonstrated significantly fewer partial-onset seizures versus placebo in adults living with epilepsy, according to a Phase III clinical study published online in Epilepsia. This study was one of three that supported the approval of Vimpat by the U.S. Food and Drug Administration (FDA) in 2008 for use as an add-on therapy for the treatment of partial-onset seizures in people...
 New guidelines developed by the American Academy of Neurology and the American Epilepsy Society show it's relatively safe for women with epilepsy to become pregnant, but caution must be taken, including avoiding one particular epilepsy drug that can cause birth defects. The guidelines are published in the April 27, 2009, print issue of Neurology®, the medical journal of the American Academy of Neurology, and will be presented April 27, 2009, at the Academy's Annual Meeting in...
ST. PAUL, Minn., April 27 /PRNewswire-USNewswire/ -- New guidelines developed by the American Academy of Neurology and the American Epilepsy Society show it's relatively safe for women with epilepsy to become pregnant, but caution must be taken, including avoiding one particular epilepsy drug that can cause birth defects. The guidelines are published in the April 27, 2009, online issue of Neurology(R), the medical journal of the American Academy of Neurology, and will be presented April 27,...
According to a new study, children of mothers who took the epilepsy drug valproate during pregnancy had lower IQs than children of mothers who used other anti-seizure medications.Valproate affected children had IQ scores up to nine points lower by age 3, Dr. Kimford Meador, the study's lead author, told the Associated Press.Women who could potentially bear children have long been advised to avoid valproate, also sold under the brand name Depakote, because it has previously been linked to...
New York mutual fund pioneer and wonder drug promoter Jack Dreyfus has died at age 95 in Manhattan, hospital officials said. Dreyfus, who gained fame and fortune as a financier who turned his mutual funds into a Wall Street institution, died Friday at New York Presbyterian Hospital/Weill Cornell Medical Center, The New York Times reported. Dreyfus was one of Wall Street's the most successful investors in the 1950s and 1960s, and has been credited with popularizing participation in the stock...
The U.S. Food and Drug Administration Thursday added 41 products to an alert about diet pills containing potentially dangerous undeclared drugs, officials said. The regulatory agency now says 69 types of diet pills contain possibly unsafe hidden drugs -- a figure that is probably less than the actual number on the market, FDA new drugs and labeling compliance Director Michael Levy said. I think it's fair to say that we have a major initiative investigation ongoing into this type of product,...
The U.S. Food and Drug Administration says it will require suicide warnings on all anti-epileptic drugs, including those used to treat other conditions. The federal agency says the warning about the risk of suicidal thoughts and suicidality will be required on all anti-epileptic drugs that are also used to treat psychiatric disorders, migraine headaches and other conditions. The warnings will appear on all prescribing information or labeling. Patients being treated with anti-epileptic drugs...
Spectrum Pharmaceuticals, Inc., (NasdaqGM:SPPI) today announced that it has filed with the FDA the supplemental NDA for FUSILEV(TM) (levoleucovorin) for injection in combination with 5-FU containing regimens in advanced metastatic colorectal cancer. FUSILEV is the only commercially available formulation comprised only of the pharmacologically active isomer of leucovorin. "Ninety percent of the more than 500 million milligrams of leucovorin used in the United States is for colorectal cancer,"...
The government yesterday began posting a list of prescription drugs under investigation for potential safety problems, in an effort to better inform doctors and patients. The first list is a bare-bones compilation naming 20 medications and the potential issue for each. It provides no indication of how widespread or serious the problems might be. This has led some consumer advocates to question its usefulness and prompted industry worries that skittish patients might stop taking a useful...
