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Latest Philadelphia chromosome Stories

2013-07-09 21:24:33

New evidence suggests that using advanced genetics technologies to monitor for remaining cancer cells after treatment may soon become an effective tool to inform treatment decisions and ultimately predict patient outcomes for patients with a particularly aggressive form of acute lymphocytic leukemia (ALL). Study results were published online today in Blood, the Journal of the American Society of Hematology (ASH). Approximately 25 to 30 percent of all adults with ALL, the second most common...

2012-12-26 12:47:29

An international team, headed by researchers at the University of California, San Diego School of Medicine, has identified a key enzyme in the reprogramming process that promotes malignant stem cell cloning and the growth of chronic myeloid leukemia (CML), a cancer of the blood and marrow that experts say is increasing in prevalence. The findings are published in the Dec. 24 online early edition of the Proceedings of the National Academy of Sciences (PNAS). Despite the emergence of new...

Rare Leukemia Drug Receives FDA Approval
2012-12-16 06:40:58

redOrbit Staff & Wire Reports - Your Universe Online The US Food and Drug Administration (FDA) has approved a new drug for the treatment of two rare forms of leukemia, including chronic myeloid leukemia (CML), various media outlets have reported. Ponatinib, a third-generation, multi-targeted tyrosine kinase inhibitor that will be marketed by Ariad Pharmaceuticals under the brand-name Iclusig, received the go-ahead on Friday, some three months before the agency was required to act on...

2012-12-10 16:55:13

Despite treatment with imatinib, a successful drug that targets chronic myeloid leukemia (CML), a deadly type of cancer, some patients may continue to be at risk for relapse because a tiny pool of stem cells is resistant to treatment and may even accumulate additional genetic aberrations, eventually leading to disease progression and relapse. These leukemia stem cells are full of genetic errors, loaded with potentially lethal breaks in DNA, and are in a state of constant self-repair. Now,...


Word of the Day
vermicular
  • Like a worm in form or movement; vermiform; tortuous or sinuous; also, writhing or wriggling.
  • Like the track or trace of a worm; appearing as if worm-eaten; vermiculate.
  • Marked with fine, close-set, wavy or tortuous lines of color; vermiculated.
  • A form of rusticated masonry which is so wrought as to appear thickly indented with worm-tracks.
This word ultimately comes from the Latin 'vermis,' worm.
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