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Latest Phosphoproteomics Stories

2014-04-18 23:04:53

Live webinar to focus on using quantitative phosphoproteomics to support the discovery and development of kinase-selective drugs. The broadcast takes place on Wednesday, May 7, 2014 at 10:00am EDT (15:00 UK BST/ GMT +1). Toronto, Canada (PRWEB) April 18, 2014 The study of phosphoproteomics represents a major leap forward in drug target and mode of action analysis: Deregulated protein kinase signaling occurs in many human diseases such as cancer, inflammatory disorders or neurodegenerative...

2012-03-28 17:20:49

Later-stage cancers thrive by finding detours around roadblocks that cancer drugs put in their path, but a Purdue University biochemist is creating maps that will help drugmakers close more routes and develop better drugs. Kinase enzymes deliver phosphates to cell proteins in a process called phosphorylation, switching a cellular function on or off. Irregularities in phosphorylation can lead to uncontrolled cell growth and are a hallmark of cancer. Many successful cancer drugs are...

2011-08-04 06:00:00

Changes in cell signaling proteins are induced at lower doses in female rats compared to males VANCOUVER, Aug. 4, 2011 /PRNewswire/ - Kinexus Bioinformatics Corporation, a world-leader in molecular intelligence research, announced today the publication of the results from a major study undertaken in collaboration with the A. W. Spears Research Center, Lorillard Tobacco Company to uncover cigarette smoke protein biomarkers. The findings appear in the Journal of Proteome Research...

2011-06-30 17:58:14

New information from fission yeast provides clues for research on cancer treatments When a cell divides, the genetic information in the chromosomes must be passed on error-free to the daughter cells. Researchers at the Friedrich Miescher Laboratory in Tbingen are studying this process using fission yeast as a model organism. In cooperation with researchers at the University of Tbingen, they succeeded in attributing additional tasks to the Aurora enzymes, which were already recognized as...

2011-02-23 06:00:00

Prediction of over 30 million human kinase-substrate interactions now available at PhosphoNET website VANCOUVER, BC, Feb. 23 /PRNewswire/ - Kinexus Bioinformatics Corporation, a world-leader in molecular intelligence research, announced another major expansion in its PhosphoNET KnowledgeBase (www.phosphonet.ca) for the study of cell communication systems. This open access, online resource for the scientific community now features data on over 93,000 experimentally-confirmed human...

2010-06-09 06:00:00

Prediction of over 4.6 million human kinase-substrate interactions available in PhosphoNET website VANCOUVER, June 9 /PRNewswire/ - Kinexus Bioinformatics Corporation, a world-leader in molecular communications research, announced major advancements in its PhosphoNET KnowledgeBase (www.phosphonet.ca) for the study of cell signalling systems. This free resource to the scientific community now features data on more than 92,000 human phosphorylation sites, including their occurrence in over 20...

2009-08-06 14:09:52

Investigators at the Burnham Institute for Medical Research (Burnham) and The Scripps Research Institute (TSRI) have made the first comparative, large-scale phosphoproteomic analysis of human embryonic stem cells (hESCs) and their differentiated derivatives. The data may help stem cell researchers understand the mechanisms that determine whether stem cells divide or differentiate, what types of cells they become and how to control those complex mechanisms to facilitate development of new...

2009-04-14 11:57:00

DENVER and CAMBRIDGE, Mass., April 14 /PRNewswire/ -- (AACR 100th Annual Meeting 2009) - Genstruct Inc., a systems biology company focused on identifying molecular mechanisms, networks and biomarkers to better develop novel therapeutics, molecular diagnostics and patient-specific therapies, today announced that the results of a joint collaboration with one of its top pharmaceutical partners will be presented at the American Association for Cancer Research's (AACR) 100th Annual Meeting 2009...


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tessitura
  • The prevailing range of a vocal or instrumental part, within which most of the tones lie.
This word is Italian in origin and comes from the Latin 'textura,' web, structure.