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Last updated on April 20, 2014 at 21:20 EDT

Latest Phosphorylation Stories

2014-04-18 23:04:53

Live webinar to focus on using quantitative phosphoproteomics to support the discovery and development of kinase-selective drugs. The broadcast takes place on Wednesday, May 7, 2014 at 10:00am EDT (15:00 UK BST/ GMT +1). Toronto, Canada (PRWEB) April 18, 2014 The study of phosphoproteomics represents a major leap forward in drug target and mode of action analysis: Deregulated protein kinase signaling occurs in many human diseases such as cancer, inflammatory disorders or neurodegenerative...

2013-03-14 12:27:46

IRVINE, Calif., March 14, 2013 /PRNewswire/ -- GeneTex, a leading manufacturer of high-quality antibodies, is pleased to announce that it will be launching new antibodies against phosphorylated Histone H2A.X and p53 designed for use with zebrafish samples. (Photo: http://photos.prnewswire.com/prnh/20111129/LA13485LOGO-b) The zebrafish is being increasingly utilized as a model organism to study DNA repair. The zebrafish genome contains nearly all of the genes involved in the different DNA...

2013-03-06 08:26:09

Prediction of over 45 million protein kinase-substrate interactions now available at PhosphoNET website VANCOUVER, March 6, 2013 /PRNewswire/ - Kinexus Bioinformatics Corporation, a world-leader in molecular intelligence research, announced a major upgrade in its PhosphoNET KnowledgeBase (www.phosphonet.ca) for the study of cell communication systems. This open-access website now features data on over 177,000 experimentally-confirmed human phosphorylation sites (P-sites) and 789,000...

2013-02-27 23:00:06

The Protein Society, the leading international society devoted to furthering research and development in protein science, announces the winners of its 2013 Awards. The awards will be conferred at the 27th Annual Symposium of The Protein Society (July 20-23, 2013, Boston, MA, USA). Baltimore, Maryland (PRWEB) February 27, 2013 The Protein Society, the leading international society devoted to furthering research and development in protein science, announces the winners of its 2013 Awards. The...

2013-02-21 11:34:39

Molecular switch promises new targets for diagnosis and therapy Fetal alcohol syndrome is the leading preventable cause of developmental disorders in developed countries. And fetal alcohol spectrum disorder (FASD), a range of alcohol-related birth defects that includes fetal alcohol syndrome, is thought to affect as many as 1 in 100 children born in the United States. Any amount of alcohol consumed by the mother during pregnancy poses a risk of FASD, a condition that can include the...

2012-12-10 08:26:26

IRVINE, Calif., Dec. 10, 2012 /PRNewswire/ -- GeneTex, a leading manufacturer of antibodies and antibody-related reagents, is set to launch a new antibody against phosphorylated Histone H3. Histone proteins package and organize the DNA of eukaryotic cells into structural units referred to as nucleosomes, and the modification of histone tails plays a critical role in the modulation of gene transcription. (Photo: http://photos.prnewswire.com/prnh/20121210/LA26278) (Logo:...

2012-08-20 11:50:56

A laboratory study led by UNC medical oncologist Stergios Moschos, MD, demonstrates how a new targeted drug, Elesclomol, blocks oxidative phosphorylation, which appears to play essential role in melanoma that has not been well-understood. Elesclomol (Synta Pharmaceuticals, Lexington, MA) was previously shown to have clinical benefit only in patients with normal serum lactate dehydrogenase (LDH), a laboratory test routinely used to assess activity of disease. For more than 60 years,...

2012-07-20 01:52:04

The research provides insights into programmed cell death and opens door to new approaches to cancer treatment Scientists at The Scripps Research Institute have simultaneously mapped two of the most important types of protein-modification in cells, revealing their extensive cooperation during an essential cellular process. Phosphorylation, the attachment of a phosphate group to a protein, and proteolysis, the cleavage of a protein, had almost always been studied independently. The new...

2012-07-06 10:22:10

℠Traffic policeman´ protein directs crucial step in cell division A traffic policeman standing at a busy intersection directing the flow of vehicles may be a rare sight these days, but a similar scene appears to still frequently play out in our cells. A protein called Lem4 directs a crucial step of cell division by preventing the progress of one molecule while waving another through, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have...

2012-06-22 16:08:18

Protein binds to growth factor receptor, priming it for normal function; Likely tie to 4 cancers Once considered merely a passive link between proteins that matter, Grb2 - pronounced "grab2" - actually lives up to its nickname with its controlling grip on an important cell signaling pathway, scientists at The University of Texas MD Anderson Cancer Center report in the June 22 issue of Cell. "Grb2 is a switch that controls normal signaling through the fibroblast growth factor receptor...