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Last updated on April 18, 2014 at 7:49 EDT

Latest Photolyase Stories

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2011-07-26 09:57:15

Researchers who have been working for nearly a decade to piece together the process by which an enzyme repairs sun-damaged DNA have finally witnessed the entire process in full detail in the laboratory. What they saw contradicts fundamental notions of how key biological molecules break up during the repair of sunburn "“ and that knowledge could someday lead to drugs or even lotions that could heal sunburn in humans. In the Proceedings of the National Academy of Sciences (PNAS), the Ohio...

2010-07-26 12:19:03

Researchers have long known that humans lack a key enzyme -- one possessed by most of the animal kingdom and even plants -- that reverses severe sun damage. For the first time, researchers have witnessed how this enzyme works at the atomic level to repair sun-damaged DNA. The discovery holds promise for future sunburn remedies and skin cancer prevention. In the early online edition of the journal Nature, Ohio State University physicist and chemist Dongping Zhong and his colleagues describe...

2009-04-14 13:59:59

U.S. researchers say they have used a plant photolyase protein to aid them in understanding the complexities of human sleep-wake cycles. The plant photolyase structure provides a much better model to use to study how the cryptochrome proteins in the human clock function than we have ever had before, said the study's lead investigator Kenichi Hitomi. It's like knowing for the first time where the engine is in a car. When you know what the most important parts of the protein are, then you can...