Latest PKM2 Stories
Researchers have caught a protein they previously implicated in a variety of cancer-promoting roles performing a vital function in cell division, survival and development of brain tumors.
Researchers at The University of Texas MD Anderson Cancer Center have tracked down a cancer-promoting protein's pathway into the cell nucleus and discovered how, once there, it fires up a glucose metabolism pathway on which brain tumors thrive.
Boosting the activity of a particular enzyme can help block tumors from growing, according to research published in Nature Chemical Biology.
Crippling a protein that allows cancer cells to grow when oxygen is scarce causes tumors to regress.
GIESSEN, Germany, October 5, 2010 /PRNewswire/ -- - Biomarker 'M2-PK' Identified as Key Enzyme in Cancer Diagnosis and Therapy - Warburg hypothesis (named after the Nobel prize winner) confirmed - Cancer cells can be recognised by their metabolism - Scientists from Harvard Medical School in Boston report on the enzyme 'M2-PK' in a study in the renowned specialist journal 'Science' - Tests for detecting M2-PK in blood or also in stool samples are already available...
In a paper appearing in the Sept. 16 online edition of Science, Matthew Vander Heiden assistant professor of biology and member of the David H. Koch Institute for Integrative Cancer Research at MIT and researchers at Harvard University report a previously unknown element of cancer cells' peculiar metabolism.
Understanding and overcoming â€˜the Warburg Effectâ€™.