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Latest Plasma protein binding Stories

2007-06-10 06:00:12

By He, Yan-Ling Sabo, Ron; Riviere, Gilles-Jacques; Sunkara, Gangadhar; Et al Key words: Drug interaction - International normalized ratio - Pharmacokinetics - Prothrombin time - Vildagliptin - Warfarin ABSTRACT Objective: Vildagliptin is a potent and selective dipeptidyl peptidase-IV (DPP-4) inhibitor that improves glycemic control in patients with type 2 diabetes by increasing alpha and beta-cell responsiveness to glucose. This study assessed the effect of multiple doses of Vildagliptin...


Word of the Day
humgruffin
  • A terrible or repulsive person.
Regarding the etymology of 'humgruffin,' the OED says (rather unhelpfully) that it's a 'made-up word.' We might guess that 'hum' comes from 'humbug' or possibly 'hum' meaning 'a disagreeable smell,' while 'gruffin' could be a combination of 'gruff' and 'griffin.'