Latest Plasmodium berghei Stories
Approximately 350 million to 500 million cases of malaria are diagnosed each year mostly in sub-Saharan Africa. While medications to prevent and treat malaria do exist, the demand for new treatments is on the rise, in part, because malaria parasites have developed a resistance to existing medications.
Bacteria in the gut of the Anopheles gambiae mosquito inhibit infection of the insect with Plasmodium falciparum, the parasite that causes malaria in humans.
Swedish scientists say they have demonstrated a rapid diagnostic malaria test can provide valuable support for healthcare in low- and mid-income countries. The procedure is based on a simple blood test and, the researchers say, helps ensure a greater number of patients receive the right treatment at no extra cost for the healthcare services. Since the existing test methods are too complicated and expensive for most primary healthcare clinics in Africa, people are prescribed malaria treatment...
British scientists say they have created chemical compounds that kill the most deadly malaria parasites, including those resistant to existing drugs. The University of Leeds researchers said the compounds work by preventing the enzyme dihydroorotate dehydrogenase, which is essential to the growth of the parasite Plasmodium falciparum, from working. Without this enzyme, Plasmodium falciparum is unable to grow and therefore it dies, said lead researcher Glenn McConkey.
Researchers at the University of Pennsylvania have discovered that parasites hijack host-cell proteins to ensure their survival and proliferation, suggesting new ways to control the diseases they cause.
Researchers at the Johns Hopkins Bloomberg School of Public Health have for the first time identified a molecular pathway that triggers an immune response in multiple mosquito species capable of stopping the development of Plasmodium falciparum
Temperature is an important factor in the spread of malaria and other mosquito-borne diseases, but researchers who look at average monthly or annual temperatures are not seeing the whole picture.
It was announced on Wednesday that scientists have tracked the genomes of the parasite that is the foundation of the majority of malaria cases outside of Africa.
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