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Latest Plasmodium falciparum biology Stories

2014-07-17 16:13:25

Washington University School of Medicine Scientists may be able to entomb the malaria parasite in a prison of its own making, researchers at Washington University School of Medicine in St. Louis report July 16 in Nature. As it invades a red blood cell, the malaria parasite takes part of the host cell's membrane to build a protective compartment. To grow properly, steal nourishment and dump waste, the parasite then starts a series of major renovations that transform the red blood cell...

Researchers Discover Achilles Heel Of The Plasmodium And Aim A Molecular Arrow To Destroy It
2014-03-12 15:01:18

Université de Genève The malaria parasite is particularly pernicious since it is built to develop resistance to treatments. The lack of new therapeutic approaches also contributes to the persistence of this global scourge. A study led by Didier Picard, professor at the Faculty of Sciences of the University of Geneva (UNIGE), Switzerland, describes a new class of molecules targeting the two problems at the same time. Using ultra sophisticated computerised modelling tools, the researchers...

2014-02-24 07:54:55

Barbara K. Kennedy, Penn State University 23 February 2014 — Two teams have independently discovered that a single regulatory protein acts as the master genetic switch that triggers the development of male and female sexual forms (termed gametocytes) of the malaria parasite, solving a long-standing mystery in parasite biology with important implications for human health. The protein, AP2-G, is necessary for activating a set of genes that initiate the development of gametocytes -- the...

Chemical Modification In Human Malaria Parasite DNA Discovered
2013-12-11 13:24:24

University of California - Riverside Findings by UC Riverside researchers could help build a new drug to kill the deadly parasite that is becoming resistant to existing drugs Say "malaria" and most people think "mosquito," but the buzzing, biting insect is merely the messenger, delivering the Plasmodium parasites that sickened more than 200 million people globally in 2010 and killed about 660,000. Worse, the parasite is showing resistance to artemisinin, the most effective drug for...

Masquerade Ball For Malaria Parasite Could Be Coming To An End
2012-12-03 12:16:51

The Hebrew University of Jerusalem Hebrew University researchers discover how the deadly malaria parasite evades the immune system and make progress toward developing a cure More than a million people die each year of malaria caused by different strains of the Plasmodium parasite transmitted by the Anopheles mosquito. The medical world has yet to find an effective vaccine against the deadly parasite, which mainly affects pregnant women and children under the age of five. By figuring out...

2012-08-01 23:07:09

The deadliest form of malaria is caused the protozoan Plasmodium falciparum. During its life-cycle in human blood, the parasite P. falciparum expresses unique proteins on the surface on infected blood cells. Antibodies to these proteins are associated with protection from malaria, however, the identity of surface protein(s) that elicit the strongest immune response is unknown. Dr. James Beeson and colleagues at the Walter and Eliza Hall Institute of Medical Research in Victoria, Australia...

2012-02-23 18:00:54

Scientists have discovered a new target in their fight against the devastating global disease 'malaria' thanks to the discovery of a new protein involved in the parasite's life cycle. The research has uncovered a vital player in the sexual phase of the malaria parasite's reproduction which could prove an effective target for new treatments to stop the disease in its tracks. The scientists from The University of Nottingham's School of Biology, with collaborators from the Universities of...

2012-02-14 11:45:07

New research from the University of Melbourne shows how the malaria parasite (Plasmodium falciparum) changes into a banana shape before sexual reproduction, a finding that could provide targets for vaccine or drug development and may explain how the parasite evades the human immune system. The work was conducted by an Australian research team led by Dr Matthew Dixon and PhD student Megan Dearnley from the Department of Biochemistry and Molecular Biology, Bio21 Institute at the University...

2012-01-25 14:34:31

The parasite that causes malaria is a genetic outlier, which has prevented scientists from discovering the functions of most of its genes. Researchers at National Jewish Health and Yale University School of Medicine have devised a technique to overcome the genetic oddity of Plasmodium falciparum, the major cause of human malaria. This new approach led them discover a new gene involved in lipid synthesis, and opens the door to further genetic discovery for the entire organism. This should...

2012-01-18 21:33:00

The discovery by researchers from the Walter and Eliza Hall Institute of a molecule that is key to malaria's 'invisibility cloak' will help to better understand how the parasite causes disease and escapes from the defenses mounted by the immune system. The research team, led by Professor Alan Cowman from the institute's Infection and Immunity division, has identified one of the crucial molecules that instructs the parasite to employ its invisibility cloak to hide from the immune system,...


Word of the Day
tessitura
  • The prevailing range of a vocal or instrumental part, within which most of the tones lie.
This word is Italian in origin and comes from the Latin 'textura,' web, structure.