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Latest Plasmodium falciparum Stories

2014-07-31 17:36:22

Wellcome Trust Drug-resistant malaria parasites have spread to critical border regions of Southeast Asia, seriously threatening global malaria control and elimination programs, according to a study published in the New England Journal of Medicine. The study confirms that resistance to the world's most effective antimalarial drug, artemisinin, is now widespread in Southeast Asia. This is not the first, or even the second time the malaria parasite has developed resistance to front line...

2014-07-30 09:55:44

Burness Communications The innovative PfSPZ Challenge is key to success for speedier testing of new malaria vaccine and drugs An international research team today reports the first-ever clinical trial demonstrating controlled malaria infection in an African nation in the modern era. The study, published online in the American Journal of Tropical Medicine and Hygiene (AJTMH) represents a significant milestone in the search for new malaria drugs and vaccines. The study establishes...

2014-07-17 16:13:25

Washington University School of Medicine Scientists may be able to entomb the malaria parasite in a prison of its own making, researchers at Washington University School of Medicine in St. Louis report July 16 in Nature. As it invades a red blood cell, the malaria parasite takes part of the host cell's membrane to build a protective compartment. To grow properly, steal nourishment and dump waste, the parasite then starts a series of major renovations that transform the red blood cell...

2014-07-02 10:26:26

Walter and Eliza Hall Institute of Medical Research Melbourne researchers are homing in on a new target for malaria treatment, after developing a compound that blocks the action of a key ‘gatekeeper’ enzyme essential for malaria parasite survival. The compound, called WEHI-916, is the first step toward a new class of antimalarial drugs that could cure and prevent malaria infections caused by all species of the parasite, including those resistant to existing drugs. Scientists at...

Single Cell Genome Sequencing Of Malaria Parasites
2014-05-11 03:52:59

Wellcome Trust Single-cell genomics could provide new insight into the biology of Malaria parasites, including their virulence and levels of drug resistance, to ultimately improve treatment and control of the disease, according to new research funded by the Wellcome Trust and the National Institutes of Health. The findings are revealed in a study by researchers at the Texas Biomedical Research Institute and published today in the journal Genome Research. Malaria infections commonly...

2014-04-29 20:27:40

ROCKVILLE, Md., April 29, 2014 /PRNewswire-USNewswire/ -- Biotechnology company Sanaria Inc.( )aims to raise at least $250,000 in 30 days on Indiegogo.com, a crowdfunding website. The campaign launches on May 6, 2014. Funds will be dedicated to the development of SporoBot(TM), a robot that will dissect mosquito salivary glands. By replacing manual microdissection of mosquito salivary glands, Sporobot(TM) will automate a key step in the manufacturing process of Sanaria(®) PfSPZ...

2014-04-18 12:07:29

Children in Mali (and many other regions where malaria is common) are infected with malaria parasites more than 100 times a year, but they get sick with malaria fever only a few times. To understand how the immune system manages to prevent malaria fever in most cases, Peter Crompton, from the US National Institute of Allergy and Infectious Diseases, and colleagues in the US and in Mali, analyzed immune cells from healthy children before the malaria season and from the same children after...

2014-04-07 13:34:30

UC Riverside-led research could help identify new anti-malaria strategies A research team led by a cell biologist at the University of California, Riverside has generated a 3D model of the human malaria parasite genome at three different stages in the parasite's life cycle — the first time such 3D architecture has been generated during the progression of the life cycle of a parasite. The parasite that causes malaria in humans is Plasmodium falciparum. The female Anopheles mosquito...

Climate Change Allows Malaria To Reach New Heights
2014-03-07 05:27:57

redOrbit Staff & Wire Reports - Your Universe Online Scientists from the London School of Hygiene & Tropical Medicine and the University of Michigan have discovered the first concrete evidence that the mosquito-borne disease malaria travels to higher elevations during warmer years and returns to lower altitudes when temperatures become cooler. In research appearing in the March 7 edition of Science, the study authors reviewed records from the highland regions of Colombia and...

2014-02-24 07:54:55

Barbara K. Kennedy, Penn State University 23 February 2014 — Two teams have independently discovered that a single regulatory protein acts as the master genetic switch that triggers the development of male and female sexual forms (termed gametocytes) of the malaria parasite, solving a long-standing mystery in parasite biology with important implications for human health. The protein, AP2-G, is necessary for activating a set of genes that initiate the development of gametocytes -- the...


Word of the Day
cruet
  • A vial or small glass bottle, especially one for holding vinegar, oil, etc.; a caster for liquids.
This word is Middle English in origin, and ultimately comes from the Old French, diminutive of 'crue,' flask.
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