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Latest Plasmodium falciparum Stories

2012-08-13 02:25:17

IRVINE, Calif., Aug. 13, 2012 /PRNewswire/ -- Antigen Discovery, Inc. (ADi) today announced that it has received a Phase II Small Business Innovation and Research (SBIR) award from the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health. The three-year award, totaling approximately $ 2.5 million, is a continuation of a Phase I SBIR grant to scan the Plasmodium falciparum proteome for protective antigens. The funds will support a collaborative...

Sequenced Malaria Genome Provides Benefits, Difficulties In Finding A Cure
2012-08-06 11:45:07

Brett Smith for redOrbit.com - Your Universe Online After sequencing the genome of several malaria-related parasites, scientists found that the protozoans responsible for the deadly disease are very genetically diverse and therefore difficult to eradicate, according to their report published this week in the journal Nature Genetics. While the genomes of the four sequenced strains of Plasmodium vivax, a parasite that infects about 100 million people each year, indicated that...

2012-08-01 23:07:09

The deadliest form of malaria is caused the protozoan Plasmodium falciparum. During its life-cycle in human blood, the parasite P. falciparum expresses unique proteins on the surface on infected blood cells. Antibodies to these proteins are associated with protection from malaria, however, the identity of surface protein(s) that elicit the strongest immune response is unknown. Dr. James Beeson and colleagues at the Walter and Eliza Hall Institute of Medical Research in Victoria, Australia...

2012-07-25 12:23:39

Research: Overdiagnosis and mistreatment of malaria among febrile patients at primary healthcare level in Afghanistan: observational study Substantial overdiagnosis and mistreatment of malaria is evident in south and central Asia, warns a study published on bmj.com today. With more than two billion people at risk of malaria in this part of Asia — larger than that of Africa - this is a major public health problem which needs to be confronted, say the authors. Malaria remains one...

Can Genetics Prevent The Transmission Of Malaria?
2012-07-17 07:52:22

redOrbit Staff & Wire Reports - Your Universe Online Malaria kills more than 800,000 people worldwide every year and many of those victims are children. Researchers are now reporting that they have genetically modified a bacterium commonly found in the mosquitos mid gut and found that the parasite that causes malaria in people does not survive in mosquitoes carrying the modified bacterium. The researchers, from the Johns Hopkins Malaria Research Institute, modified the bacterium...

2012-07-04 22:53:53

In most comprehensive review of a decade of data researchers confirm indoor insecticide treatments, dramatically reduce malaria; study finds world´s best drug still effective in African malaria 'hot zone' while researchers question for how long A pair of provocative studies in the July 2012 issue of The American Journal of Tropical Medicine and Hygiene (AJTMH) provides a window into the intense ground war now underway against malaria. In one review, researchers offer new evidence...

2012-06-13 14:23:28

ROCKVILLE, Md., June 13, 2012 /PRNewswire-USNewswire/ -- Sanaria Inc., a privately held company in Rockville, Maryland, and the Institute for Bioscience and Biotechnology Research (IBBR) of the University of Maryland College Park announce the receipt of a multi-year Phase II Small Business Innovation Research (SBIR) Grant from the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH). The grant, worth nearly $3 million over a 3 year...

Mosquitoes Incapable Of Transmitting Malaria Created
2012-06-12 13:10:31

Advance provides genetic options for controlling spread of deadly disease Mosquitoes bred to be unable to infect people with the malaria parasite are an attractive approach to helping curb one of the world´s most pressing public health issues, according to UC Irvine scientists. Anthony James and colleagues from UCI and the Pasteur Institute in Paris have produced a model of the Anopheles stephensi mosquito – a major source of malaria in India and the Middle East – that...

2012-06-05 11:21:11

A new technique that accurately determines the risk of infants in endemic countries developing clinical malaria could provide a valuable tool for evaluating new malaria prevention strategies and vaccines. The technique could even help to understand how anti-malarial vaccine and treatment strategies act to reduce malaria, say researchers from the Walter and Eliza Hall Institute, Swiss Tropical and Public Health Institute, University of Basel and the Papua New Guinea Institute of Medical...

2012-05-23 20:24:10

A novel anti-inflammatory drug could help to improve survival in the most severe cases of malaria by preventing the immune system from causing irrevocable brain and tissue damage. Walter and Eliza Hall Institute researchers have shown that a new class of anti-inflammatory agents, called IDR (innate defense regulator) peptides, could help to increase survival from severe clinical malaria when used in combination with antimalarial drugs. A research team fronted by Dr Ariel Achtman and Dr...