Latest Plasmodium falciparum Stories
Scientists have discovered a new target in their fight against the devastating global disease 'malaria' thanks to the discovery of a new protein involved in the parasite's life cycle.
In this week's PLoS Medicine, Michael Delves of Imperial College London, UK and colleagues compare the activity of 50 current and experimental antimalarials against liver, sexual blood, and mosquito stages of selected human and nonhuman parasite species, including Plasmodium falciparum, Plasmodium berghei, and Plasmodium yoelii.
New research from the University of Melbourne shows how the malaria parasite (Plasmodium falciparum) changes into a banana shape before sexual reproduction, a finding that could provide targets for vaccine or drug development and may explain how the parasite evades the human immune system.
A study of almost 3,800 pregnancies has provided the most accurate and direct evidence to date that malaria infection reduces early foetal growth.
Malaria is a parasite disease that is passed from one human to another by the bite of infected Anopheles mosquitoes. The parasites enter the blood stream and infect red blood cells.
The parasite that causes malaria is a genetic outlier, which has prevented scientists from discovering the functions of most of its genes.
A new suite of malaria maps has revealed in unprecedented detail the current global pattern of the disease, allowing researchers to see how malaria has changed over a number of years.
The discovery by researchers from the Walter and Eliza Hall Institute of a molecule that is key to malaria's 'invisibility cloak' will help to better understand how the parasite causes disease and escapes from the defenses mounted by the immune system.
In the event that a vaccine for the prevention of malaria is licensed and ready for use (such as the research malaria vaccine RTS,S, which currently looks promising), distributing and giving the vaccine to three-month old infants via the World Health Organization's Expanded Programme on Immunization (EPI) will be the most efficient mechanism in high transmission areas but for lower transmission areas, mass vaccination every 5 years might be a more efficient vaccination strategy, a new study...
Researchers from Boston College have discovered a protein that plays a pivotal role in the progression of the deadly diseases toxoplasmosis and malaria and shown that its function could be genetically blocked in order to halt the progress of the parasite-borne illnesses, the team reports in the current edition of the journal Science.
- Large; stout; burly.