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Latest Plasmodium falciparum Stories

2011-10-06 09:11:27

Study in Benin, Africa finds indoor spraying with the insecticide bendiocarb reduced infectious mosquito bites to near zero; and offers effective tool for malaria control strategy in areas rife with pyrethroid-resistance Indoor spraying with the insecticide bendiocarb has dramatically decreased malaria transmission in many parts of Benin, new evidence that insecticides remain a potent weapon for fighting malaria in Africa despite the rapid rise of resistance to an entire class of...

2011-09-27 15:02:32

Researchers at the Perelman School of Medicine at the University of Pennsylvania, Monash University, and Virginia Tech have used a set of novel inhibitors to analyze how the malaria parasite, Plasmodium falciparum, uses enzymes to chew up human hemoglobin from host red blood cells as a food source. They have validated that two of these parasite enzymes called peptidases are potential anti-malarial drug targets. The research appeared in the Aug. 15 early online issue of the Proceedings of the...

2011-09-09 13:32:33

Vaccine is first of its kind to earn FDA approval to test in humans For the first time, a malaria vaccine that uses the entire malaria parasite has proven safe and shown promise to produce a strong immune response in a clinical trial, according to a new study co-authored by researchers at the University of Maryland School of Medicine Center for Vaccine Development. The vaccine is unique in that it employs the entire malaria parasite, while most experimental malaria vaccines consist of just...

2011-09-08 20:52:53

Using live but weakened malaria parasites as the basis of a vaccine represents a potentially encouraging anti-malaria strategy, according to results of follow-up animal studies performed after the conclusion of a recent clinical trial in humans. The research was conducted by scientists at the Vaccine Research Center (VRC) of the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, working in concert with a large team of collaborators. The findings...

2011-09-07 12:42:55

Interventions targeting malaria, such as insecticide-treated bed nets, antimalarial drugs and mosquito control, could substantially reduce cases of bacteraemia, which kill hundreds of thousands of children each year in Africa and worldwide. This is the conclusion of research published today in the Lancet and funded by the Wellcome Trust. Researchers at the KEMRI-Wellcome Trust Research Programme in Kilifi, Kenya, examined two major killer diseases, malaria and bacteraemia, or invasive...

2011-09-01 11:58:38

An investigation into the mysterious inner workings of the malaria parasite has revealed that it survives and proliferates in the human bloodstream thanks in part to a single, crucial chemical that the parasite produces internally. According to scientists at the University of California, San Francisco (UCSF) and Stanford Medical School, reporting today in the journal PLoS Biology, this insight immediately provides a powerful new tool for discovering and designing drugs to treat malaria,...

2011-08-31 12:39:54

A novel technique to "tame" the malaria parasite, by forcing it to depend on an external supply of a vital chemical, has been developed by researchers at the Stanford University School of Medicine and the University of California-San Francisco. The scientists have, in effect, created a domesticated strain of Plasmodium – the one-celled parasite that causes malaria – that would no longer cause this dreaded disease. Their findings not only make it possible to grow large volumes...


Word of the Day
snash
  • To talk saucily.
  • Insolent, opprobrious language; impertinent abuse.
This word is Scots in origin and probably imitative.