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Latest Plasmodium Stories

2012-01-25 14:34:31

The parasite that causes malaria is a genetic outlier, which has prevented scientists from discovering the functions of most of its genes. Researchers at National Jewish Health and Yale University School of Medicine have devised a technique to overcome the genetic oddity of Plasmodium falciparum, the major cause of human malaria. This new approach led them discover a new gene involved in lipid synthesis, and opens the door to further genetic discovery for the entire organism. This should...

2012-01-18 21:33:00

The discovery by researchers from the Walter and Eliza Hall Institute of a molecule that is key to malaria's 'invisibility cloak' will help to better understand how the parasite causes disease and escapes from the defenses mounted by the immune system. The research team, led by Professor Alan Cowman from the institute's Infection and Immunity division, has identified one of the crucial molecules that instructs the parasite to employ its invisibility cloak to hide from the immune system,...

2012-01-12 21:53:48

Genome sequencing helps identify essential protein in disease-carrying parasites Researchers from Boston College have discovered a protein that plays a pivotal role in the progression of the deadly diseases toxoplasmosis and malaria and shown that its function could be genetically blocked in order to halt the progress of the parasite-borne illnesses, the team reports in the current edition of the journal Science. The protein, identified as DOC2.1, plays a similar role in the secretion...

2012-01-09 11:28:02

Because the protein is found in the parasite but not in humans, it is ideal target for an anti-malarial drug A biology lab at Washington University has just cracked the structure and function of a protein that plays a key role in the life of a parasite that killed 655,000 people in 2010. The protein is an enzyme that Plasmodium falciparum, the protozoan that causes the most lethal form of malaria, uses to make cell membrane. The protozoan cannot survive without this enzyme, but even...

2011-12-23 10:16:23

Researchers at the Johns Hopkins Malaria Research Institute have demonstrated that the Anopheles mosquito's innate immune system could be genetically engineered to block the transmission of malaria-causing parasites to humans. In addition, they showed that the genetic modification had limited impact on the mosquito's fitness under laboratory conditions. The researchers' findings are published December 22nd in the Open Access journal PLoS Pathogens. In this study, Dimopoulos and his team...

Only Few Seabird Species Contract Avian Malaria
2011-12-13 04:02:07

Climate differences have less impact on the transmission of blood parasites than expected Seabirds often live in large colonies in very confined spaces. Parasites, such as fleas and ticks, take advantage of this ideal habitat with its rich supply of nutrition. As a result, they can transmit blood parasites like avian malaria to the birds. Scientists from the Max Planck Institute for Ornithology in Radolfzell and a team of international colleagues have investigated whether this affects all...

2011-12-08 10:26:42

An antimalarial agent developed by researchers at Albert Einstein College of Medicine of Yeshiva University proved effective at clearing infections caused by the malaria parasite most lethal to humans — by literally starving the parasites to death. The novel research, carried out on a small number of non-human primates, could bolster efforts to develop more potent therapies against one of the world's leading killers. The study, published in the November 11, 2011 issue of PLoS ONE, was...

2011-12-01 19:15:34

Finding has implications for effectiveness of potential vaccines A mutation on the surface of human red blood cells provides protection against malaria caused by the parasite Plasmodium vivax, research led by Case Western Reserve University School of Medicine shows. The minute change, at a single position of red blood cell surface protein called the Duffy blood-group antigen, has been known for years. But the researchers found this difference makes it harder for the parasite to lock...

Breakthrough In The Battle Against Malaria
2011-11-30 05:54:45

Study identifies new ways to kill the human malaria parasite, Plasmodium falciparum An international team of scientists has announced a breakthrough in the fight against malaria, paving the way for the development of new drugs to treat the deadly disease. According to the World Health Organisation malaria currently infects more than 225 million people worldwide and accounts for nearly 800,000 deaths per year. Most deaths occur among children living in Africa where a child dies every 45...

2011-11-18 03:52:02

New class of compounds would target earliest stages of infection Researchers have discovered a group of chemical compounds that might one day be developed into drugs that can treat malaria infection in both the liver and the bloodstream. The study, which appears in the Nov. 18 issue of Science, was led by Elizabeth A. Winzeler, Ph.D., of the Scripps Research Institute in La Jolla, Calif., and was partially funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of...


Word of the Day
mundungus
  • A stinking tobacco.
  • Offal; waste animal product; organic matter unfit for consumption.
This word comes from the Spanish 'mondongo,' tripe, entrails.