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Latest Platelet-derived growth factor Stories

2012-03-06 11:11:26

New research in the FASEB Journal demonstrates that a balanced delivery of genes for angiogenic factors safely grows new blood vessels in mice A new research discovery by a team of Stanford and European scientists offers hope that people with atherosclerotic disease may one day be able to avoid limb amputation related to ischemia. A new research report appearing online in the FASEB Journal suggests that the delivery of genes for two molecules naturally produced by the body, called...

2012-02-06 08:36:43

(Ivanhoe Newswire) -- Thousands of individuals are diagnosed with Glioblastoma mutiforme (GMB) each year and given little hope of survival. Sadly this is one of the most difficult forms of brain cancer to treat and the most common. Due to the aggressive nature of GMB there have been few successful therapies for the treatment of this form of brain cancer.  A team at the University of California in San Francisco lead by Joanna Philips, and Zena Werb has discovered a possible new...

2012-02-01 15:57:40

Glioblastoma multiforme (GBM) is the most common of all malignant brain tumors that originate in the brain. Patients with GBM have a poor prognosis because it is a highly aggressive form of cancer that is commonly resistant to current therapies. New therapeutic approaches are therefore much needed. Joanna Phillips, Zena Werb, and colleagues, at the University of California, San Francisco, have now identified a potential new therapeutic target for the treatment of GBM. A substantial...

2011-11-14 23:16:11

Glioblastoma multiforme (GBM) is the most common malignant brain cancer in humans. Patients with GBM have a poor prognosis because it is a highly aggressive form of cancer that is commonly resistant to current therapies. A team of researchers -- led by Bo Hu and Shi-Yuan Cheng, at the University of Pittsburgh Cancer Institute, Pittsburgh -- has now identified a molecular pathway that drives the aggressive cancerous nature of a substantial proportion of glioblastomas; specifically, those that...

2011-10-17 16:30:00

Scientists may someday be able to develop therapies that target this pathway to treat or prevent a variety of diseases, including diabetes as reported by DiabeticLive.com. Orlando, FL (PRWEB) October 17, 2011 For those who have diabetes, there is hope for new treatments and possible a cure. A new molecular pathway related to the regeneration of beta cells in the pancreas has been discovered by a team of researchers at the Stanford University School of Medicine. Scientists may someday be...

2011-10-12 23:15:46

By manipulating a well-known molecular pathway, JDRF-funded scientists breathe new life into aging beta cells As a person ages, the ability of their beta cells to divide and make new beta cells declines. By the time children reach the age of 10 to 12 years, the ability of their insulin-producing cells to replicate greatly diminishes. If these cells, called beta cells, are destroyed–as they are in type 1 diabetes–treatment with the hormone insulin becomes essential to regulate...

2011-10-12 23:13:14

Researchers at the Stanford University School of Medicine have identified a key molecular pathway responsible for the natural decrease in the proliferation of insulin-producing cells that occurs as a person ages. Artificially activating this pathway, which is normally not functional in adults, may be a new way to combat diabetes. "We're hopeful that soon we might be able to manipulate this pathway in a therapeutic way in humans," said professor of developmental biology Seung Kim, MD, PhD,...

2011-06-09 15:09:04

Published in inaugural issue of the Journal of Parkinson's Disease Few treatments for Parkinson's disease (PD) restore function for extended periods. In a new study published today in the inaugural issue issue of the Journal of Parkinson's Disease, an international group of researchers report that platelet-derived growth factor-BB (PDGF-BB) restored function in rodents and shows promise as a clinical candidate drug for treatment of PD. Parkinson's disease is the second most common...

2010-10-06 17:32:26

Platelet derived growth factor (PDGF) plays role in heart regeneration In research that one day may lead to the discovery of how to regenerate tissue damaged by heart disease, investigators at Childrens Hospital Los Angeles have identified PDGF as a key factor in the proliferation and transformation of epicardial cells, one type of cell that surrounds heart muscle and contributes to vessels. The study was published online September 21 in advance of the publication of the Proceedings of the...


Word of the Day
call-note
  • The call or cry of a bird or other animal to its mate or its young.
'Call-note' is newer than 'bird-call,' which originally referred to 'an instrument for imitating the note of birds' but now also refers to 'the song or cry of a bird.'
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