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Latest PLoS Biology Stories

2011-06-15 13:30:29

Genes control everything from eye color to disease susceptibility, and inheritance - the passing of the genes from generation to generation after they have been duplicated - depends on centromeres. Located in the little pinched waist of each chromosome, centromeres control the movements that separate sister chromosomes when cells divide ensuring that each daughter cell inherits a complete copy of each chromosome. It has long been known that centromeres are not formed solely from DNA; rather,...

2011-05-25 13:57:19

New information has come to light explaining how injured skin cells and touch-sensing nerve fibers coordinate their regeneration during wound healing. UCLA researchers Sandra Rieger and Alvaro Sagasti found that a chemical signal released by wounded skin cells promotes the regeneration of sensory fibers, thus helping to ensure that touch sensation is restored to healing skin. They discovered that the reactive oxygen species hydrogen peroxide, which is found at high concentrations at wounds,...

2011-05-04 12:44:59

Using simple robots to simulate genetic evolution over hundreds of generations, Swiss scientists provide quantitative proof of kin selection and shed light on one of the most enduring puzzles in biology: Why do most social animals, including humans, go out of their way to help each other? In next week's issue of the online, open access journal PLoS Biology, EPFL robotics professor Dario Floreano teams up with University of Lausanne biologist Laurent Keller to weigh in on the oft-debated...

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2011-05-04 09:25:00

The human eye long ago solved a problem common to both digital and film cameras: how to get good contrast in an image while also capturing faint detail. Nearly 50 years ago, physiologists described the retina's tricks for improving contrast and sharpening edges, but new experiments by neurobiologists at University of California, Berkeley and the University of Nebraska Medical Center in Omaha show how the eye achieves this without sacrificing shadow detail. These details will be published next...

2011-04-27 11:42:43

Laboratory reports success in blocking the lethal effects of ALS Brandeis researchers have made a significant advance in the effort to understand amyotrophic lateral sclerosis (ALS) by successfully reversing the toxicity of the mutated protein in the familial type of the disease. Currently there is no cure or prevention for the disease, which affects nerve cells in the brain and the spinal cord. Most frequently referred to as Lou Gehrig's disease, after its most famous victim, ALS typically...

2011-04-27 11:35:24

Several genes have been linked to ALS, with one of the most recent called FUS. Two new studies in PLoS Biology, one from the University of Pennsylvania School of Medicine, and the other from colleagues at Brandeis University, both examined FUS biology in yeast and found that defects in RNA biology may be central to how FUS contributes to ALS, or Lou Gehrig's disease. These findings point to new targets for developing drugs. Proteins aggregate to form insoluble clumps in the brain and spinal...

2011-04-20 15:05:19

Intracellular transport mechanism dissected In a multicellular organism, different cells fulfill a range of diversified functions. Often such specialization depends on the delivery of molecular goods to distinct places within a cell. It ensures that particular functions only occur at defined cellular sites. This establishment of intracellular asymmetry in the otherwise fluid environment of the cell cytoplasm requires active transport processes. Messenger RNAs (mRNA) represent an especially...

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2011-04-20 14:14:12

A massive database cataloging the human genome's functional elements -- including genes, RNA transcripts, and other products -- is being made available as an open resource to the scientific community, classrooms, science writers, and the public, thanks to an international team of researchers. In a paper published in the journal PLoS Biology on 19 April 2011, the project -- called ENCODE (Encyclopedia Of DNA Elements) -- provides an overview of the team's ongoing efforts to interpret the human...

2011-04-20 13:02:09

HudsonAlpha is part of international team releasing massive dataset The international team of the ENCODE, or Encyclopedia Of DNA Elements project, has created an overview of its ongoing large-scale efforts to interpret the human genome sequence. The April 19 publication of "A User's Guide to the Encyclopedia of DNA Elements (ENCODE)" in the journal PLoS Biology provides a guide for using the vast amounts of high-quality data and resources produced so far by the project. All of the data, tools...

2011-04-06 11:50:30

Scientists studied the global influence of human population on corals reefs and were surprised to find that highly diverse reef fish systems are the most vulnerable to human threats In an unprecedented collaborative analysis published in the journal PLoS Biology, scientists from 49 nations demonstrated that the ability of reef fish systems to produce goods and services to humanity increases rapidly with the number of species. However, growing human populations hamper the ability of reefs to...


Latest PLoS Biology Reference Libraries

PLoS Medicine
2012-05-17 15:12:48

PLoS Medicine is a peer-reviewed medical journal established in October 2004. It is the second journal of the Public Library of Sciences, which publishes open-access material. All material in PLoS Medicine is published under the Creative Commons license. To fund the journal, the publication’s business model requires that authors pay publication costs. PLoS Medicine provides an innovative and influential venue for research and comment on the major challenges to human health worldwide. It...

PLoS Biology
2012-05-02 19:40:12

PLoS Biology is a peer-reviewed scientific journal covering all aspects of biology. It was established in 2003, with the first issue published in October of that year. It was the first journal of the Public Library of Science. As of May 2012, the current editor-in-chief is Jonathan Eisen (University of California, Davis). All content in PLoS Biology is published under the Creative Commons “by-attribution” license. The journal is funded by authors who are charged set fees to publish...

PLoS ONE
2012-04-30 14:56:25

PLoS ONE is an open-access peer-reviewed scientific journal published by the Public Library of Science (PLoS). It was established in 2006 as a beta version. In August 2008 it moved from a weekly publication schedule to a daily one, publishing articles as soon as they became ready. In October 2008, it came out of “beta.” In September 2009, PLoS ONE made full online usage of every published article publicly available. The founding managing editor was Chris Surridge. He was succeeded by...

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Word of the Day
pungle
  • To take pains; labor assiduously with little progress.
This word comes from the Spanish 'pongale,' put it.
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