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2012-12-19 13:54:54

There is little evidence from real world situations in low-and-middle income countries to support the effectiveness and financial value of five interventions recommended by the World Health Organization (WHO) to control tuberculosis, which may be a reason why these interventions have not been implemented in many countries, according to a study by international experts published in this week's PLOS Medicine. Over the past few years, WHO has recommended that countries implement several...

2012-12-12 15:40:08

Outbreaks of infectious diseases, such as swine flu (H1N1) threaten global health and should be considered by funding agencies and humanitarian organizations as development issues rather than emergency situations, requiring long-term support and investment, according to US experts writing in this week's PLOS Medicine. The authors from several US institutions, led by Tiffany Bogich from Princeton University, reached these conclusions by reviewing nearly 400 serious international public...

2012-12-12 15:35:56

Measures of uncertainty should be taken into account when estimating progress towards Millennium Development Goal 4 (to reduce the mortality rate of children under 5 years by two thirds from the 1990 level by 2015) in order to give more accurate assessments of countries' progress, according to a study published in this week's PLOS Medicine. Leontine Alkema and Jin Rou New from the National University of Singapore used a statistical method called bootstrapping to calculate uncertainty...

2012-11-21 12:51:19

Models used for predicting the likelihood of individuals developing chronic kidney disease and for predicting disease progression in people who already have the condition are useful tools but not yet robust enough to help inform clinical guidelines, according to a study published in this week's PLOS Medicine. Chronic kidney disease is a common but serious condition which can lead to kidney failure. The condition cannot be cured but progression of the disease can be slowed by controlling...

2012-11-21 12:49:36

A rapid test for tuberculosis (TB) could help to reduce TB deaths, improve TB treatment, and also offer reasonably good value for money if introduced in southern Africa, an area that has high rates of HIV and a type of TB that is resistant to some drugs (multi-drug resistant TB), according to a study published in this week's PLOS Medicine. The World Health Organization (WHO) recently recommended the use of a new diagnostic test for TB (the Xpert MTB/RIF test), which can show a result...

2012-11-14 14:36:46

In this week's PLOS Medicine, Sabine Gabrysch from the University of Heidelberg, Germany and colleagues draw upon a literature review, expert survey, and consensus method to recommend new signal functions to monitor and track facilities' provision of routine and emergency newborn care. While there are currently several indicators of emergency obstetric care (EmOC) that can track and monitor a health service's capacity to respond to important obstetric complications, there are none for most...

2012-11-14 14:30:31

Early changes in liver function detected by novel techniques can identify severe infection (sepsis) hours after onset and so could have important implications for the treatment of patients who are critically ill, according to a groundbreaking study by European researchers published in this week's PLOS Medicine. Almost half of all people who develop severe sepsis die as this life-threatening condition often develops quickly and is often diagnosed too late to save the patient's life. In...

2012-11-14 13:04:56

In malaria-endemic countries, 350 million people are predicted to be deficient in an enzyme that means they can suffer severe complications from taking primaquine, a key drug for treating relapsing malaria, according to a study funded by the Wellcome Trust and published in this week's PLOS Medicine. This finding is important as primaquine is recommended in the global action plan to eliminate malaria and is the only drug to prevent malaria relapse. The benefits of implementing a treatment...

2012-10-03 10:20:35

Both obesity and under-nutrition are common in women and children from the Western Sahara living in refugee camps in Algeria, highlighting the need to balance both obesity prevention and management with interventions to tackle under-nutrition in this population, according to a study by international researchers published in this week's PLOS Medicine. The authors, led by Carlos Grijalva-Eternod and Andrew Seal from the UCL Institute of Child Health in London, surveyed 2005 households in...

2012-10-03 10:17:22

Strategies implemented in high-income countries to improve blood glucose control in people with type 1 diabetes and so reduce complications, such as heart attacks, strokes, and early death, are working, but there is much need for further improvement, according to a study from Scotland published in this week's PLOS Medicine. Using information from national databases representing over 20 000 patients from 2005 to 2008, Scottish researchers led by Helen Colhoun from the University of Dundee,...


Latest PLoS Medicine Reference Libraries

PLoS Medicine
2012-05-17 15:12:48

PLoS Medicine is a peer-reviewed medical journal established in October 2004. It is the second journal of the Public Library of Sciences, which publishes open-access material. All material in PLoS Medicine is published under the Creative Commons license. To fund the journal, the publication’s business model requires that authors pay publication costs. PLoS Medicine provides an innovative and influential venue for research and comment on the major challenges to human health worldwide. It...

PLoS Biology
2012-05-02 19:40:12

PLoS Biology is a peer-reviewed scientific journal covering all aspects of biology. It was established in 2003, with the first issue published in October of that year. It was the first journal of the Public Library of Science. As of May 2012, the current editor-in-chief is Jonathan Eisen (University of California, Davis). All content in PLoS Biology is published under the Creative Commons “by-attribution” license. The journal is funded by authors who are charged set fees to publish...

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Word of the Day
mallemaroking
  • Nautical, the visiting and carousing of sailors in the Greenland ships.
This word is apparently from a confusion of two similar Dutch words: 'mallemerok,' a foolish woman, and 'mallemok,' a name for some persons among the crew of a whaling vessel.