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2013-12-04 10:41:23

Half of trials with results posted in ClinicalTrials.gov database have not been published in a journal, and for some that have, the database contains more information The trial registry ClinicalTrials.gov, which permits posting of trial results, includes results of some trials that have not been published in a peer-reviewed journal and in some cases includes more information than published trials, according to Carolina Riveros (INSERM, Paris, France) and colleagues, authors of a PLOS...

2013-12-04 10:38:28

An analysis of patients from across the malaria endemic world suggests that a key antimalarial treatment could be improved by better dosing in young children Antimalarial drug resistance has hampered malaria control programs for almost 60 years. A key factor in combatting this threat is to ensure that all antimalarial drugs are deployed in a way that ensures that the maximum number of patients are completely cured. A study published this week in PLOS Medicine explores this issue by...

2013-11-13 10:40:49

A study published this week in PLOS Medicine reveals profound systemic dysregulation of the immune response induced by RSV infection in young children and suggest that molecular markers might be able to predict disease severity. RSV is responsible for a substantial fraction of serious respiratory infections and deaths among young children worldwide and a top candidate for vaccine development. A team of researchers led by Asuncion Mejias and Octavio Ramilo, both from The Research...

2013-11-13 10:39:29

A study published this week in PLOS Medicine suggests that epigenetic modification of the HAND2 gene plays a critical role in the development of endometrial cancer. HAND2 is active in the healthy endometrium (the tissue lining the uterus) where it antagonizes the growth-inducing effects of estrogen. By contrast, in more than 90% of endometrial cancers, the gene has undergone hypermethylation, an epigenetic modification that doesn't change its DNA sequence but renders it inactive. Martin...

2013-10-30 10:05:35

In middle-income countries such as China, interventions that have a psychological or social component (often referred to as psychosocial interventions) delivered by health workers who are not mental health specialists could help women during the perinatal period, according to a study published this week in PLOS Medicine. The results of the study, conducted by Kelly Clarke and colleagues, from the University College London in the UK, found that psychological and health promotion...

2013-10-16 11:33:08

A scientific study calculating Iraqi deaths for almost the complete period of the US-led war and subsequent occupation published in PLOS Medicine this week reports that close to half a million Iraqi deaths are directly or indirectly attributable to the conflict. A team of researchers from Iraq and the US led by Amy Hagopian, of the University of Washington, conducted a survey in 2000 households across Iraq and used the data to estimate death rates for the two year-period before the war began...

2013-10-09 11:45:55

In this week's PLOS Medicine two independently written articles call for a shift away from the leader-centric approach that polio eradication campaigns are currently pursuing in the three countries (Nigeria, Pakistan and Afghanistan) where the disease remains endemic. In a Policy Forum article, authors from Nigeria, Pakistan and Afghanistan led by Seye Abimbola from the National Primary Health Care Development Agency, Nigeria, argue that the global health community and governments involved...

2013-10-09 11:43:40

The current influenza (flu) vaccination policy in England and Wales should be expanded to target 5 to 16-year-olds in order to further reduce the number of deaths from flu, according to a study by UK researchers published in this week's PLOS Medicine. The results of the study by Marc Baguelin and colleagues from the London School of Hygiene & Tropical Medicine in the UK, Public Health England, and Athens University of Economics and Business, show that the current flu vaccination policy...

2013-10-02 12:05:01

Community health officers (health workers who are not trained midwives) can safely give injections of the drug oxytocin to prevent severe bleeding after delivery (postpartum hemorrhage) when attending home births in rural areas of Ghana, according to a study by US and Ghanaian researchers in this week's PLOS Medicine. The researchers, led by Cynthia Stanton from the Johns Hopkins Bloomberg School of Public Health in the US, also found that oxytocin injections halved the risk of postpartum...

2013-09-25 10:27:28

Acupuncture or counseling, provided alongside usual care, could benefit patients with depression, according to a study by researchers at the University of York. The study, conducted by a team led by Dr Hugh MacPherson, of the Department of Health Sciences at York, found that in a primary care setting, combining acupuncture or counseling with usual care had some benefits after three months for patients with recurring depression. Published this week in PLOS Medicine, the study, which also...


Latest PLoS Medicine Reference Libraries

PLoS Medicine
2012-05-17 15:12:48

PLoS Medicine is a peer-reviewed medical journal established in October 2004. It is the second journal of the Public Library of Sciences, which publishes open-access material. All material in PLoS Medicine is published under the Creative Commons license. To fund the journal, the publication’s business model requires that authors pay publication costs. PLoS Medicine provides an innovative and influential venue for research and comment on the major challenges to human health worldwide. It...

PLoS Biology
2012-05-02 19:40:12

PLoS Biology is a peer-reviewed scientific journal covering all aspects of biology. It was established in 2003, with the first issue published in October of that year. It was the first journal of the Public Library of Science. As of May 2012, the current editor-in-chief is Jonathan Eisen (University of California, Davis). All content in PLoS Biology is published under the Creative Commons “by-attribution” license. The journal is funded by authors who are charged set fees to publish...

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Word of the Day
cock-a-hoop
  • Exultant; jubilant; triumphant; on the high horse.
  • Tipsy; slightly intoxicated.
This word may come from the phrase 'to set cock on hoop,' or 'to drink festively.' Its origin otherwise is unclear. A theory, according to the Word Detective, is that it's a 'transliteration of the French phrase 'coq a huppe,' meaning a rooster displaying its crest ('huppe') in a pose of proud defiance.' Therefore, 'cock-a-hoop' would 'liken a drunken man to a boastful and aggressive rooster.'
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